SYNTHESIS, CHARACTERIZATION, ANTIMICROBIAL, CNS AND ANALGESIC STUDIES OF 2-[N-(4-chloro-2-{[1-(2-hydroxyphenyl) ethylidene]amino} phenyl) ethanimidoyl] phenol AND ITS COMPLEXES

4-Chloro-O-Phenylene diamine and its Copper (II) complex have been prepared by the Schiff base formation. The synthesized compound was confirmed from UV IR & NMR spectrum. The O-Phenylene diamine and its Copper (II) complex found to have remarkable antimicrobial activity due to the presence of nitrogen group.The antimicrobial activities of three bactericidal organisms Bacillus subtilis Streptococcus viridians and Staphylococcus epidermidis on the test compounds 4-Chloro-O-Phenylene diamine and its Copper (II) complex were screened by employing the Disc Diffusion method. A concentration gradient (500 1000 2000 and 3000g) of each compound was put into study. From the study it is obse...