THERMOKINETIC STUDIES OF PRODUCTION OF L-ASPARAGINASE BY BACILLUS LICHENIFORMIS IN BATCH FERMENTATION.
- Department of Bio-Engineering, Birla Institute of Technology, Mesra, Ranchi, Jharkhand, India.
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Microbial L-Asparaginase having potential application in the chemotherapy of acute lymphoblastic leukemia. Present study was carried out to study the thermokinetics of L-Asparaginase from Bacillus licheniformis. Enzyme production was carried out at different temperature and pH for different duration of time. The kinetics of biomass formation, product formation and substrate utilization was carried out at different conditions. The maximum L-Asparaginase activity of 2.9 U/ml was observed after the 24 hrs of post inoculation. The maximum specific growth rate was calculated and found to be 0.2209 h-1. The productivity was found to be 0.574 U g cell-1 h-1..
[Raikamal Bhattacharya, Hare Ram Singh and Santosh Kumar Jha. (2016); THERMOKINETIC STUDIES OF PRODUCTION OF L-ASPARAGINASE BY BACILLUS LICHENIFORMIS IN BATCH FERMENTATION. Int. J. of Adv. Res. 4 (Jun). 1670-1677] (ISSN 2320-5407). www.journalijar.com
