30Apr 2016

A facile one pot synthesis of pyrazolyl pyrimidines through multcomponent reaction

  • Department of Chemistry, A.V.V.M. Sri Pushpam College, Poondi -613 503 India.
  • Department of Chemistry, Periyar EVR College, Tiruchirappalli-620 023 India.
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A series of new pyrimidine derivatives containing pyrazole moiety were designed and synthesized. In addition, various substituents were introduced in to the entering pyrazole aldehyde ring and ?-keto ester with the purpose of exploring the influence of substituent on anticancer activity by regulating the electronic and steric effects. The synthesized compounds were characterized by various spectroscopic techniques.

[Manickam. Pramesh, Selvaraj. Jayanthi, Ragunathan.Venkatachalam and Bathey. R. Venkatraman. (2016); A facile one pot synthesis of pyrazolyl pyrimidines through multcomponent reaction Int. J. of Adv. Res. 4 (Apr). 995-1001] (ISSN 2320-5407). www.journalijar.com

Manickam. Pramesh, Selvaraj. Jayanthi, Ragunathan.Venkatacha

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Article DOI: 10.21474/IJAR01/271      
DOI URL: https://dx.doi.org/10.21474/IJAR01/271

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