A review: Recent investigations on Quinazoline Scaffold
- Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Jamia Hamdard New Delhi-110062, India.
- College of Pharmacy, Shree Ganpati Institute of Technology Ghaziabad-201302, UP, India
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The aim of this review is to endow with an outline of assorted pharmacological activities of quinazoline moiety. Quinazoline have drawn an enormous consideration owing to their extended applications in the area of medicinal chemistry. It has become a fashionable subject up of two fused six-membered aromatic ring system, a benzene ring and a pyrimidine ring due to its assorted uses. It is showed for its different Pharmacological activities and compounds with diverse substitutions convey together to acquaintance of a target with considerate of the molecule types that might interact with the target receptor. Quinazolines are a huge type of pharmacologically active compounds that showed a broad spectrum of pharmacological activities such as anticancer, anticonvulsant, anti-inflammatory, anti-microbial, antimalarial, anti-HIV, antioxidant, antifungal, antibacterial, anti-mutagenic, anti-depressant, anti-leishmanial, anti-leukemic activities. The aim of this review is to assemble literature work showed by researchers on Quinazoline for their diverse pharmacological activities and also reported current efforts made on this molecule.
[Jahangir Alam, Ozair Alam, Mohd Javed Naim, Perwaiz Alam (2015); A review: Recent investigations on Quinazoline Scaffold Int. J. of Adv. Res. 3 (Dec). 1656-1664] (ISSN 2320-5407). www.journalijar.com
