Attenuating role of Trévo dietary supplement on hormonal toxicity induced by caffeine in albino rats
- Department of Biology, Cross River State College of Education, Akamkpa, Nigeria.
- Department of Genetics and Biotechnology, University of Calabar, Calabar, Nigeria.
- Abstract
- Keywords
- Cite This Article as
- Corresponding Author
The attenuating role of Trévo dietary supplement (TDS), a multi-herbal health drink on caffeine induced hormonal toxicity in albino rats was studied. Thirty healthy male albino rats of 12 weeks old were divided into five groups with six rats in each group using a completely randomized design (CRD). The experimental animals were treated with combinations of caffeine and TDS orally. The treatment lasted for 65 days. Results indicated statistically significant (P<0.05) reduction in the serum levels of testosterone, follicle stimulating hormone (FSH), luteinizing hormone/interstitial cell stimulating hormone (LH/ICSH) and estradiol in caffeine treated rats. However, TDS effectively attenuated the caffeine induced toxicities on the hormonal milieu in a dose-dependent manner. These results shows that TDS is effective in attenuating caffeine induced hormonal toxicity in albino rat models.
[Uno, U. U., Ekaluo, U. B., Okoi, E. P., Ogbe, H. O. and Peter, N. (2015); Attenuating role of Trévo dietary supplement on hormonal toxicity induced by caffeine in albino rats Int. J. of Adv. Res. 3 (Nov). 586- 590] (ISSN 2320-5407). www.journalijar.com
