Invitro Anticancer Activity of Hedychium coronarium Against Human Breast Cancer Cell Line MCF-7

Hedychium coronarium Koen. (Family Zingiberaceae), popularly named butterfly ginger, is widely available in tropical and subtropical regions. The purpose of this study was to test in vitro anticancer activities of the hexane, chloroform and methanolic extracts of Hedychium coronarium against the human breast cancer cell lines [MCF-7]. The Average values of (Hexane, Chloroform and Methanolic concerntrations) of Hedychium coronarium were shown in (Table 1), Out of which Methanol Average values was found to be more 10:100, 20:100, 40:100,80:94.2) than Hexane and Methanolic concerntrations.Agraph was plotted between different concentrations of Hedychium coronarium (Hexane, Chloroform and Methanolic concerntrations) had different cytotoxicity effects on MCF7 cell line (Figure 1), In the present study ,Methanol treatment on cell growth of drug-sensitive and Adriamycin-resistant MCF-7 cells where, maximum inhibition was observed. The plant extract investigated in this study have significant anticancer activity against the breast cancer cell lines tested. Further investigation is required to isolate and elucidate the structure of the compounds responsible for the observed activity.