Natural cycle versus new artificial protocol in frozen embryo transfer

Background: preparation of the endometrium for better receptivity and implantation is important step for high pregnancy rate in frozen cycle embryo transfer for ICSI procedures. Many methods known for preparation but which the best still a debatable issue. The present study is represent a fixed dose sequential artificial cycle. Material and methods: 80 cases scheduled for frozen cycle transfer divided into two groups group one (natural cycle) monitored only by ultrasound and when leading follicle reached 20mmhCG injection given and embryos transferred .group two received progynova2 tablets twice per daily for 8 days from the first day menses then uterogestan tablets added three times per day for 5 days the embryo transfer done at the fourteenth day. Quantitative hCG done after 14 days. Results: On comparing endometrial thickness and pregnancy rate among studied groups group two (augmented fixed cycle) showed pregnancy rate 62.25% compared to 37.5% in group one with p value <0.02(statistically significant difference as shown in (table 2). Conclusion: the new method of endometrial preparation for frozen embryo transfer is better than natural cycle preparation.