31Aug 2015

Oral Contraceptive In Women With Polycystic Ovary Syndrome : Influence on Behavioural Changes

  • (MBBS, DNB OBS GYN) Departments of Obstetrics & Gynecology , NIMS University, JAIPUR (Rajasthan).
  • (MBBS, MS OBS GYN) Departments of Obstetrics & Gynecology , NIMS University, JAIPUR (Rajasthan).
  • (MBBS, DNB OBS GYN) Departments of Obstetrics & Gynecology , NIMS University, JAIPUR (Rajasthan).
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Women with polycystic ovary syndrome (PCOS) have gynecologic, psychological , reproductive and metabolic co-morbidities that affects their entire lifespan. They have higher risk of depression. Limited data are available regarding effects of an oral contraceptive pills (OC) treatment on health-related quality of life (HRQOL). AIM We aimed to determine the impact of an (OC) treatment on health-related quality of life (HRQOL), depressive and anxiety symptoms in polycystic ovary syndrome (PCOS). METHOD Prospective observational study. Study included 84 patients with PCOS without a previous psychiatric diagnosis. Category I included Oral contraceptive users and Category II included Non Contraceptive users. All participants evaluated after 6 months of treatment with EE/DRSP (3 mg/30 ?g). RESULTS After treatment, regular menstrual cycles were attained and hirsutism was significantly improved in all patients (P< 0.05 for both). Percentage of women with behavioural score improvement after treatment with OC pills (CAT-1) was higher than non users of OC pills. CONCLUSION OC therapy in PCOS improves hirsutism and menstrual disturbances, along with HRQOL. This improvement is not associated with any change in the prevalence of depressive and anxiety symptoms.


[KUNJAN HITESHKUMAR SHAH, BHAGWANDAS GUPTA, RAKSHA SHARMA (2015); Oral Contraceptive In Women With Polycystic Ovary Syndrome : Influence on Behavioural Changes Int. J. of Adv. Res. 3 (Aug). 490-496] (ISSN 2320-5407). www.journalijar.com


DR KUNJAN HITESHKUMAR SHAH