MANAGEMENT OF LOW BLOOD PRESSURE DURING SPINAL ANAESTHESIA FOR CAESAREAN SECTION: COMPARISON BETWEEN EPHEDRINE AND LOW-DILUTE NOREPINEPHRINE
Chiguer Chaimae
, Raja Amine
, Fattah Ayoub
, Afif Amine
, El Harit Marouane
, El Yousoufi Smael
and Salmi Said
- ICU of the Maternity Service, Department of Resuscitation and Anesthesia, University Hospital Ibn Rochd, Casablanca, Morocco.
- Abstract
- Cite This Article as
- Corresponding Author
This prospective study, conducted over six months at the Ibn Rochd University Hospital in Casablanca, compared the efficacy of weakly diluted norepinephrine and ephedrine for the management of hypotension induced by spinal anesthesia during caesarean sections. Among 120 patients (mean age: 25.5 5.5 years), norepinephrine was distinguished by improved hemodynamic stability, ensuring more precise heart rate control (maximum of 97.47 bpm vs. 133.7 bpm) and higher systolic blood pressure (126.19 mmHg vs. 80.84 mmHg), while optimally preserving the pH of umbilical cord blood (7.25 versus 7.21). Despite comparable gasometric parameters and Apgar scores between groups, a dose of 16 mcg norepinephrine demonstrated slightly better hemodynamic control than that of 8 mcg. These results suggest that weakly diluted norepinephrine represents a safer and more effective therapeutic alternative to ephedrine in this clinical setting, thus ensuring better maternal and fetal safety.
[Chiguer Chaimae, Raja Amine, Fattah Ayoub, Afif Amine, El Harit Marouane, El Yousoufi Smael and Salmi Said (2025); MANAGEMENT OF LOW BLOOD PRESSURE DURING SPINAL ANAESTHESIA FOR CAESAREAN SECTION: COMPARISON BETWEEN EPHEDRINE AND LOW-DILUTE NOREPINEPHRINE Int. J. of Adv. Res. (Mar). 464-475] (ISSN 2320-5407). www.journalijar.com
ICU of the maternity service, Department of Resuscitation and Anesthesia, University Hospital Ibn Rochd, Casablanca, Morocco
Morocco
