CLINICAL STUDY OF EFFECTIVENESS OF THE AMRITADYAGUGGULU IN HYPERLIPIDEMIA (MEDHOROGA)

Hyperlipidemia is a medical condition characterized by an increase in one or more of the plasma lipids. According to classical writings, Ayurveda referred to hyperlipidemia as Medo Roga.The purpose of the study was to study the effect of Amritadyagugguluonhyperlipidemia. Methodology: Study was Randomized, Comparative clinical study. with duration of the  eight weeks and two months follow up period. 44 Patients were selected randomly from outdoor patient department of Swastavrittaclinic, National Ayurveda Teaching Hospital, Borella. Treatment effectiveness is based on subjective and objective parameters. The University of Colombos Institute of Indigenous Medicine was provided ethical clearance. Total cholesterol, Triglyceride, HDL, LDL, VLDL and Risk Ratio in Lipid profile were assessed beforeand after the treatment. Results: The majority of them were between age of 50 and 59 i.e. 36.4%. All were married, with females accounting for 79.5%. Most of the participants were Buddhist (90.9%) and Sinhala (93.2%). The large amounts, 75%, lived in urban areas. There was a family history of hyperlipidemia in 33.3%. Amrithadyaguggulu significantly reduced total cholesterol (p<0.01), LDL (p<0.05), and risk ratio (p<0.05). Significant reduction in BMI and weight (p<0.01). Results showed substantial changes in systolic and diastolic blood pressure levels before and after treatment(p<0.01). Symptoms of hyperlipidemia included thirst (Thrusha), hunger (Kshuth), daytime sleepiness (Swapna), hyperhidrosis (Ati Sweda), and offensive body odor (Daugandya), lack of body strength (Daurbalya) and difficulty in breathing (KshudraShwasa)were greatly reduced (p<0.001), except for Impaired or decreased Sexual Performance (AlpaMaithuna) (p>0.05). The present study concluded as Amritadyaguggulu had significant result on elevated lipid profile and symptoms of in hyperlipidemic patients.