STUDY OF FACTORS AFFECTING SARCOPENIA IN TYPE 2 DIABETES MELLITUS

Patients with type 2 diabetesmellitus frequently developed sarcopenia, a chronic complication, and prior research produced conflicting findings regarding the incidence and risk factors of sarcopenia in T2DM.

Objectives:Thisstudy aims to determine frequency of sarcopenia in patients with Type 2 Diabetes Mellitus and to determine factors affecting sarcopenia in patients with Type 2 Diabetes Mellitus

Methods: After applying the inclusion and exclusion criteria, 151 T2DM patients were included in the cross sectional study that was carried out in hospitals attached to Bangalore Medical College and Research Institute. The patients baseline information was documented in a predefined format and patients were screened for presence of sarcopeniausing SARC-F (sluggishness, assistance in walking, rising from a chair, climb stairs, falls) score. Different groups were compared using chi square/ ANOVA /t-test according to the type of data. All the parameters were compared between patients with and without sarcopenia. P value < 0.05 was considered statistically significant. R version 4.1.2 statistical software was used for the statistical analyses.

Results:The study included 151 T2DM patients in total. Sarcopenia was common among T2DM patients, with 38% prevalence. Elderly age, female gender, chronic hyperglycemia (higher HbA1c), and hypertension were all significant risk factors for sarcopenia.

Conclusion:Patients with T2DM often experienced sarcopenia. Significant risk factors for Sarcopenia included advanced age, female gender, hypertension, chronic hyperglycemia, and a diet low in nutrients.