30Dec 2024

PROTEIN-PROTEIN INTERACTION PREDICTION USING A DEEP NEURAL NETWORK WITH BATCH NORMALIZATION AND QUARTILE ALGORITHM

  • Assistant Professor, Department of Computer Science, Esatic, Cote Divoire.
  • Assistant Professor, Department of Computer Science, Esatic, Cote Divoire.
  • Assistant Professor, Department of Computer Science, Una, Cote Divoire.
  • Professor, Department of Computer Science, Esatic, Cote dIvoire.
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Detecting protein-protein interactions (PPIs) is key for disease therapy development. While experimental methods are costly, deep neural network (DNN) models now use available PPI data for prediction, though limited by low-quality sequence-based data. This study introduces FDPPI, a DNN model leveraging a quartile-based algorithm and batch normalization to enhance performance, achieving 98.09% accuracy, 98.34% precision, and 97.72% sensitivity on human PPI data.


[N. Diffon Charlemagne Kopoin, Alex Armand Josue Akohoule, Wielfrid Morie and Olivier Pascal Asseu (2024); PROTEIN-PROTEIN INTERACTION PREDICTION USING A DEEP NEURAL NETWORK WITH BATCH NORMALIZATION AND QUARTILE ALGORITHM Int. J. of Adv. Res. (Dec). 750-760] (ISSN 2320-5407). www.journalijar.com


Kopoin N'Diffon Charlemagne
Ecole Supérieure Africaine des Technologies de l'Information et de la Communication
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DOI:


Article DOI: 10.21474/IJAR01/20074      
DOI URL: https://dx.doi.org/10.21474/IJAR01/20074