31Dec 2024

CHRONIC NEUTROPENIA REVEALING HYPER IGM SYNDROME: A CASE REPORT

  • Pediatrics Department, Mohammed V Military Instruction Hospital, Rabat.
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Hyper IgM syndrome is a well-knownhereditaryimmunodeficiency, first describedin 1961. It iscaused by a defect in B lymphocytes, characterized by a normal or high serumlevel of IgM and a low or zerolevel of IgG, IgA, IgE resultingfrom a deficiency in isotype switching. Itsclinical manifestations are dominated by recurrent infections, especiallyrespiratory and digestive. The interest of this article is to illustrate a particular mode of revelation of hyper IgM syndromes through persistent chronicneutropenia in an infant.

[E. Bahous, R. Abilkassem, A. Radi, M. Kmari, A. Hassani and A. Agadr (2024); CHRONIC NEUTROPENIA REVEALING HYPER IGM SYNDROME: A CASE REPORT Int. J. of Adv. Res. (Dec). 912-915] (ISSN 2320-5407). www.journalijar.com

BAHOUS El mehdi
pedtarics
Morocco

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