Relationship of Body Mass Index and Hormonal disturbance in patients with Polycystic Ovary Syndrome.

Polycystic ovary syndrome (PCOS) and obesity are commonly seen in women of reproductive age . The study includes 50 infertile Iraqi women with polycystic ovary syndrome (PCOS) and 20 healthy women, Blood samples were collected from the Infertility center of AL-Yarmok Teaching Hospital in Baghdad / Iraq. The age of PCOS women and healthy women was ranged from 16 to 45 years. The results were as follows: There is significant (P <0.05) decrease in E2 levels 34.90 ± 2.39 pg/ml and FSH levels 7.0 ± 0.41 ?IU/ml in PCOS women. There is significant (P<0.05) increase in LH levels 13.51 ± 3.88 ?IU/ml in PCOS women and there is no significant differences in Testosterone levels 1.50 ± 0.30 ng/ml . The ratio of LH/FSH was >1.5 but no significantly . The hormonal profile according to BMI was as follows: There is no significant (P <0.05) decrease in E2 levels in overweight PCOS women 29.8 ± 3.0 pg/ml compared with normal weight but no obese PCOS women .Testosterone was significant increase in obese and overweight PCOS women 1.3 ± 0.5 ; 1.2 ± 0.15 ng/ml respectively .There is significant (P <0.05) decrease in FSH level in both overweigh and obese PCOS women 7.9 ± 0.7 ; 5.96 ± 0.43 ?IU/ml respectively.