20Jul 2022

ANALYSIS OF CORRELATION OF STROMAL CD10 EXPRESSION INCARCINOMABREASTNOSTYPEWITH HER2/NEU

  • Assistant Professor, DepartmentofPathology,Government Mohankumaramangalam Medical College,Salem,/TamilNaduDr.MGRMedicalUniversity,Chennai,India.
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Background:Breastcancerisoneofthemostcommoncanceramongwomen.Stromaplaysanimportantpathogeneticroleincarcinomaofbreast.Stromalmarkercouldbeusedforassessingtheprognosisofbreastcancer.

Methods:30invasiveductalcarcinomaofbreastNOStypewereselected.Hematoxylinandeosinstainingwasdone.ImmunohistochemistrywasdonewithCD10,andHER2.CD10expressioninstromawasstudiedandstatisticallyanalyzedwithHER2.

Results:strongpositivityforstromalCD10wasobservedin46%(14outof30)ofcases.10outof14(71%)CD10positivecasesshowedHER2/neu positivity.CD10expressionwassignificantlyassociatedHER2/neupositivity.

Conclusions:StromalCD10expressionisdirectly correlatedwithHER2receptorpositivity.CD10couldbeusedasnew prognosticmarkerincarcinomaofbreast.

[S. Ulaganathan, Abu Arshad A. and R. Duraisamy (2022); ANALYSIS OF CORRELATION OF STROMAL CD10 EXPRESSION INCARCINOMABREASTNOSTYPEWITH HER2/NEU Int. J. of Adv. Res. 10 (Jul). 212-217] (ISSN 2320-5407). www.journalijar.com

S.Ulaganathan
Assistant professor,Department of Pathology, Government mohankumaramangalam medical college ,Salem,/ TamilNadu Dr.MGR Medical University,Chennai,India
India

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Article DOI: 10.21474/IJAR01/15022      
DOI URL: https://dx.doi.org/10.21474/IJAR01/15022

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