TO ACESS LEVEL OF CA 19.9( CARBOHYDRATE ANTIGEN 19.9) & CA125 (CARBOHYDRATE ANTIGEN 125) IN PATIENTS OF CANCER ( OVARIAN, ENDOMETRIAL & PANCREATIC)

Purpose: To investigate the diagnostic value of CA 19.9 & CA125 in patients of cancer.

Methods: 100 randomly selected patients coming to Medicine & Gynae OPD with symptoms of cancer. Serum was taken and CA19.9 & CA 125 was analyzed by Electrochemiluminescent Immunoassay.

Results: It showed serum levels of CA19.9 & CA125 of patient with malignant ovarian, endometriosis & pancreatic tumor significantly higher than the control group. Out of total 50 patients for CA19.9, 45 were females & 5 males. Out of 45 females, 14 females & 3 males have raised value. All 3 males have significantly raised value more than 500 U/ml & All 3 had pancreatic carcinoma. Out of 14 females those had value more than 1000 had features of malignancy whereas rest females of value more than 100 had features of endometriosis. For CA125 total of 50 patients were taken out of which only 10 patients had raised CA125 level. All were females and 60% had value more than cut off that was 35u/ml. Out of the 10 females who had raised CA125, 6 had carcinoma & metastasis & rest 4 had endometriosis.