POTENTIAL ROLE OF PUNICA GRANATUM JUICE FOR TREATING DENGUE FEVER ON CYCLOPHOSPHAMIDE INDUCED SWISS ALBINO MICE

The present work aims at analysing the potential of pomegranate juice which is used for the treatment of dengue fever as it is used in increasing the bodys immune power by increasing the platelets count. The phytochemical characteristics of pomegranate juice extract is studied and compared with papaya leaf juice extract. Both the papaya leaves and pomegranate are naturally and easily available, which are non toxic, has no side effects. In our study, the effectiveness of pomegranate juice was studied by introducing the juice into cyclophosphamide induced swiss albino mice. Before the administration, the platelet count, White Blood Cells (WBC) and Red Blood Cells (RBC) was analysed, after the induction of cyclophosphamide platelet count and white blood cells decreased from 9,74,200, 11380 to 8,42,400, 6140 and no significance for RBC. The blood samples were rechecked after introduction of pomegranate juice extract. It was observed that platelet count, WBC increased significantly, but there was no significant increase in RBC. Therefore, it can be concluded that pomegranate juice significantly increases the platelet count and WBC.