ORAL CYCLOSPORINE IN PATIENTS WITH SEVERE ACUTE ULCERATIVE COLITIS

- Hepato-Gastroenterology Department, Hassan II University Medical Center, Fez, Morocco, Faculty of Medicine, Sidi Mohammed Ben Abdellah University, Fez Morocco.
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Ulcerative colitis (UC) is a chronic inflammatory bowel disease characterized by intermittent exacerbations and remissions. About 15% of patients with UC will have a severe flare of their disease requiring hospitalization. Unfortunately, approximately 30% of patients admitted with severe ulcerative colitis fail intravenous steroids and require surgery or a second-line therapy. Oral cyclosporine has been reported to be useful in inducing remission in patients with corticoresistant severe UC. We present our experience of its use in fourteen patients.
[H. Abid, H. Laarabi, M. Lahlali, A. Lamine, N. Lahmidani, M. Elyousfi, D. Benajah, A. Ibrahimi and M. Elabkari (2020); ORAL CYCLOSPORINE IN PATIENTS WITH SEVERE ACUTE ULCERATIVE COLITIS Int. J. of Adv. Res. 8 (Sep). 683-686] (ISSN 2320-5407). www.journalijar.com
Morocco