Study of the Efficacy of Aloe Vera Extracts in Treatment of Non-Infected Wounds Induced by Sulferric Acid and Infected Wounds with Staphylococcus aureus.

S. aureus poses an important problem in hospitals, nursing homes, and other health care settings. Serious infections due to these organisms currently necessitate the use of non-?-lactam antibacterial therapy. H2SO4 comes from strong poisons, because the symptom poison appears after five minutes from apple on skin. If possible treatment by Na2Co3 as antidot for H2SO4, but the necrosis or bacterial infection cases should by use drugs. Aloe vera gel is used topically for its anti-inflammatory and wound-healing properties, but it has also been used internally as a general tonic.The aim of this study is to evaluate the efficacy of aloe vera extract to treatment of normally induced and infected wounds with Staphylococcus aureus . In this study Twenty rabbits were used in this experiment. All of these rabbits were males. Burning techniques: These animals were divided in four groups and burning induced by H2SO4. After 1 hour of washing with distilled water, group 1 was still without treatment , group 2 was treated with aloe Vera extract for 7 days, group 3 was infected with staphylococcus aurous and group 4 was infected with staphylococcus aureus and aloe Vera extract for 14 days. Re-isolation of bacteria: Swabs were taken from all experimented burns every 24 hours before and after treatment to detect the progress of infection and recovery respectively. The result appeared whilst signs of burns and infected animals were recorded after 24–48 hours of infection as redness, ulceration, edematous and thickening of skin tissue was shown in non infected group I. The extract used for group II of non infected animals showed some signs after nearly 2 days, however after 7 days the wound progressed to healing and there was no swelling and ulceration. The skin began to soften and there was no cracked tissue. Infected group III, with staphylococcus aureus, showed thickening areas and swelling with pus cell. Group IV was infected with staphylococcus aureus and treated with aloe Vera extract for 14 days. There was not any inflammation areas caused by bacteria pus cell and swelling and they showed a degree of healing. While Histopathological sections appeared in the skin of the rabbits at 14 days, post-wound of the extracts shows granulation tissue in the wound area, irregular fibrous connective tissue proliferation with congested blood vessel, as well as mononuclear cell infiltration in some areas and an edematous. These results in the present study prove that aloe Vera extracts have the ability to accelerate burn healing time and act as an antibacterial through inhibition. Staphylococcus aureus were experimentally infected in burns and therefore are recommended to be used for treatment of wounds and burns .