25Sep 2019

VIRECHANA IN VITILIGO: A RAY OF HOPE.

  • PG Scholar, Dept of Panchakarma, Rishikul Campus UAU, Haridwar.
  • PG Scholar, Dept of Panchakarma, Rishikul Campus UAU, Haridwar.
  • Head, Dept of Panchakarma, Rishikul Campus UAU, Haridwar.
  • Professor, Main Campus UAU, Dehradun.
  • Assistant Professor, Rishikul Campus UAU, Haridwar.
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  • Abstract
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Skin not only protects our body but also form a major interface between man and the environment. Vitiligo is an autoimmune disorder characterized by white depigmented spots typically first observed on the fingers, knuckles, around eyes and mouth. Vitiligo is an acquired condition effecting 2% of the population worldwide. In Ayurveda the vitiligo can be considered asShvitraand it is caused by imbalance of tridoshas. Sthana of Bhrajak pitta istwak and should be maintained in proper state, imbalance to this may lead to skin disease. This disease is more than just a simple cosmetic problem. Due to the chronic nature, long term treatment, lack of uniform effective therapy and unpredictable course the disease is usually very demoralizing for patients. Various treatment modalities available in contemporary system of medicine but, these are time consuming and some even have adverse effects. So, it becomes a challenge to provide effective and safe treatment protocol for vitiligo. Ayurvedicapproach is by maintaining Bhrajak Pitta.


  1. Sehgal VN. Vitiligo. Textbook of clinical dermatology. 4th edition. Jaypee: New Delhi; 2004.p. 99-101
  2. Hann SK, Park YK, Chun WH. Clinical feature of vitiligo. Clin Dermatol 1997; 15:891-7
  3. Howitz J, Brodthagen H, Scheartz M, Thomsen K. Prevalence of Vitiligo. Epidemiological survey on the isle of Bornholm, Denmark. Arch Dermatol 1977; 113:47-52
  4. ManjiriWalinjkar, PD Londhe, SR Makhare, Anil Avhad: Clinical Efficacy of DhatryadiGhanavati in Shvitra (Vitiligo) Manjiri; Journal of Ayurveda and Integrated Medical Sciences | Nov - Dec 2016 | Vol. 1 | Issue 4 14
  5. Genetics & Incidence, [cited on 2016 MAY 11].Available from; http://www.vitiligosupport.org/ vitiligo/genetics and incidence.cfm
  6. Levai M. A study of certain contributory factors in the development of vitiligo in South Indian patients. AMA Arch Derm 1958;78: 364-71.
  7. Sir Stanley Davidson, Davidson?s principle and practice of medicine, Elsevier publications, 11th edition Page no.1253.
  8. Srivastava G. Vitiligo- Introduction Asian Clinic. Dermatol 1994; 1:11-5
  9. Acharya Susruta, Susruthasamhithanidanasthana 5th chapter, sloka no.17, ChoaukhambaSurbharathiprakashan,Varnasi page no 286
  10. Acharya Kasyapa, Kashyapa Samhita, chikitsastana 9th chapter, shloka 2, ChaukhambaVisvabharati, Varanasi, page no-198
  11. Acharya Charaka, Charakasamhitha, Chikitsasthana 7thchapter, Sloka no 4-8, ChaukhambaSurbharathiprakashan,Varnasi, Page no-450
  12. Chaudhary Soniya, Mishra Pramod, Sharma Brahmanand, SoniAnamika: International Journal of Applied Ayurved Research ?MANAGEMENT OF KILASA (SHVITRA) W.S.R. TO VITILIGO? ISSN: 2347- 6362???? IJAAR VOLUME II ISSUE 11 JAN-FEB 201
  13. Schallreuter KU., Moore J, Behrens WillaimsS, Panske A, Harari M. rapid initiation of re- pigmentation in vitiligo with dead sea climatotherapy in combination with pseudo catalase. Int Journal 2002; 41:482-7
  14. Ortonne JP, Nordlund J. Mechanisms that cause abnormal skin color. In: Nordlund JJ, Boissey RE, Hearing VJ, King RA, Oetting WS, Ortonne JP, editors. The Pigmentary System: Physiology and Pathophysiology. Oxford: Blackwell Scientific Publishing; 2006. p. 521-38.
  15. Nordlund JJ, Ortonne J. The normal color of human skin. In: Nordlund JJ, Boissey RE, Hearing VJ, King RA, Oetting WS, Ortonne JP, editors. The Pigmentary System: Physiology and Pathophysiology. Oxford: Blackwell Scientific; 2006. p. 504-20.
  16. Boissy R, Nordlund JJ. Vitiligo: Current medical and scientific understanding. G Ital Dermatol et Venereol 2011. p. 46
  17. Majumder PP, Nordlund JJ, Nath SK. Pattern of familial aggregation of vitiligo. Arch Dermatol 1993; 129:994-8.[PUBMED]??[FULLTEXT]
  18. Puri N, Mojamdar M, Ramaiah A. Growth defects of melanocytes in culture from vitiligo subjects are spontaneously corrected in vivo in repigmenting subjects and can be partially corrected by the addition of fibroblast-derived growth factors in vitro. Arch Dermatol Res 1989; 281:178-84. [PUBMED]
  19. Le Poole IC, Yang F, Brown TL, Cornelius J, Babcock GF, Das PK, et al, altered gene expression in melanocytes exposed to 4-tertiary butyl phenol (4-TBP): upregulation of the A2b adenosine receptor 1. J Invest Dermatol 1999; 113:725-31
  20. Palermo B, Campanelli R, Garbelli S, Mantovani S, Lantelme E, Brazzelli V, et al, Specific cytotoxic T lymphocyte responses against Melan-A/MART1, tyrosinase and gp100 in vitiligo by the use of major histocompatibility complex/peptide tetramers: The role of cellular immunity in the etiopathogenesis of vitiligo. J Invest Dermatol 2001; 117:326-32.
  21. Al'Abadie MS, Warren MA, Bleehen SS, Gawkrodger DJ. Morphologic observations on the dermal nerves in vitiligo:an ultrastructural study. Int J Dermatol 1995; 34:837-40.
  22. Behl PN, Aggarwal A, Srivastava G. Vitiligo In: Behl PN, Srivastava G, editors. Practice of Dermatology. 9 th ed. CBS Publishers: New Delhi; 2003. p. 238-41.
  23. Fargnoli MC, Bolognia JL. Pentachrome vitiligo. J Am AcadDermatol 1995; 33:853-6.
  24. Agnivesh, Charaka, Dridhabala (1993) Charaksamhita. ChaukhambhaBharati Academy, Varanasi chikitsathana 7: 162-177.
  25. Shastri L. Asthang-Sangraha, BaidyanathAyurvedBhavan Pvt. Ltd. 1989, 1st Edition, Nidansthana - Kushthakriminidan 14/39 - 41, Pg No. 491
  26. Agnivesh, Charaka, Dridhabala (1993) Charaksamhita. ChaukhambhaBharati Academy, Varanasi chikitsathana 7: 162-177
  27. Madhavkar (1994) Madhavnidana. Chaukhambha Sanskrit Sansthan, Varanasi Kushthanidanam 39: 164.
  28. Madhavkar (1994) Madhavanidana. ChaukhambhaChaukhambha Sanskrit Sansthan, Varanasi 37: 164.
  29. Shastri N. MadhavNidanam, MotilalBanarasidas, 1st Edition (Repritnt) 2002, Kushthakriminidan,. 49/37-39 Pg. No. 633.
  30. Fauci AS, Harrison TR (1998) Harrison?s Principles of Internal medicine. 14th Edition, McGraw-Hill 316-317.
  31. Acharya YT editor. Charaka Samhita of Agnivesha; Sutra Sthana 28/11. Varanasi: ChaukhambaSurbharatiPrakashan; Reprint 2011.p.179.
  32. Agnivesha, Charaka, Dridhabala, Charakasamhita, edited by Acharya YadavjiTrikamji, Reprint ed. Varanasi; ChaukhambaSurabharatiPrakashan; 2011:458
  33. Salim Musa Mulla; Vitiligo-Ayurvedic Treatment Approach; Journal of Clinical and Cosmetic Dermatology ISSN 2576-2826 ,Published: 08 Jun, 2018, Volume 2 - Issue 3 | DOI: http://dx.doi.org/10.16966/2576-2826.129,
  34. ShastriAmbikadatta, editor. Sushrutsamhita, Ayurveda-tattvasandipika Hindi commentary (chikitsasasthan chapter 9 verse 16-43) Vol 1 14 .Varanasi: Chaukhambha Sanskrit Sansthan; 1998. P300- 304
  35. TripathiBramanand, editor .AstanagaHridayam, Nirmala HinidCommentory? (nedansasthan Chapter 14, verse 4- ,3741)10 ed .Varanasi : Choukhambha Sanskrit Pratisthan;1995. P 527,533.

[Pretya Juyal, Lalita Sharma, K.K Sharma, Alok Kumar Srivastava and Parul Sharma. (2019); VIRECHANA IN VITILIGO: A RAY OF HOPE. Int. J. of Adv. Res. 7 (Sep). 1055-1060] (ISSN 2320-5407). www.journalijar.com


Dr. Pretya


DOI:


Article DOI: 10.21474/IJAR01/9757      
DOI URL: http://dx.doi.org/10.21474/IJAR01/9757