12Jul 2019

HISTOPATHOLOGICAL SPECTRUM OF NON-NEOPLASTIC LESIONS IN UTERINE CERVIX - A ONE YEAR RETROSPECTIVE STUDY.

  • Senior resident, Department of pathology, Govt. Medical College Jammu(J&K), India.
  • Assistant professor ,Department of pathology, Govt. Medical College Jammu(J&K), India.
Crossref Cited-by Linking logo

  • Abstract
  • Keywords
  • References
  • Cite This Article as
  • Corresponding Author

Background: The uterine cervix is a gateway to many neoplastic and non-neoplastic lesions. Non-neoplastic lesions of cervix constitute a wide variety of lesions in the hysterectomy or cervical biopsy specimen. Most of these lesions are commonly seen in women of reproductive age group. The aim of the current study was to analyze the prevalence and histological types of various non-neoplastic lesions of the cervix. Materials and methods: The present retrospective study includes 200 non-neoplastic cervical lesions which were analyzed from either hysterectomy or cervical biopsy specimens received in the Department of Pathology, Government Medical College Jammu over a period of one year. All the slides of cervix were retrieved from histopathology slide records and were reviewed. Whenever required the blocks were retrieved and recut of the sections were done. Results: The study includes 300 cases of non-neoplastic cervical lesions received as a part of hysterectomy or cervical biopsy and categorized into a variety of lesions. The most common lesion was inflammatory, reactive or reactive 224 (74.6%) cases followed by glandular hyperplasia in 44 (14.6%) cases, metaplasia in 22 (7.4%) cases and benign neoplasm in 10 (3.4%) cases. Conclusion: The spectrum of cervical lesions is vast and therefore early detection, categorization and management of certain lesions can help in preventing the complications and reducing the morbidity.

  1. Nwachokor FN, Forae GC. Morphological spectrum of non-neoplastic lesions of the uterine cervix in Warri, South-South, Nigeria. Niger J Clin Pract 2013;16:429-32.
  2. International Agency for Research on Cancer. IARC Handbooks of Cancer Prevention, Vol. 10. Lyon, France: IARC, 2005. [Cited 2018 March 03].
  3. Omoniyi-Esan OG, Osasan SA, Ojo OS. Non-neoplastic diseases of the cervix in Nigeria: A histopathological study. Afr Health Sci 2006;6:76-80.
  4. Pallipady A, Illanthody S, Vaidya R, Ahmed Z, Suvarna R, Metkar G. A Clinico-Morphological Spectrum of the Non-Neoplastic Lesions of the Uterine Cervix at AJ Hospital, Mangalore. J Clin Diagn Res 2011;5: 546-50
  5. Chakraborty P, Roy A, Bhattacharya S, Addhya S, Mukherjie S. Tuberculous cervicitis: A clinicopathological and bacteriological study. J Indian Med Assoc 1995;93:167-8.
  6. Mostafa MG, Srivannuboon s, Rachanawutanon M. Accuracy of cytological findings in abnormal cervical smears by cytohistologic comparison. Indian J Pathol Microbiol 2000;43(10):23-29.
  7. Siimionescu C, Margaritescu CL, Georgescu CV, Mogoanta L, Marinescu AM. Pseudo-tumoral lesions of the cervix. Rom J MorpholEmbryol 2005;46:239-47.
  8. Manek S. Benign mimics of cervical cancers. J Diagn Pathol 2015;10:1-13.
  9. Olutoyin G, Omoniyi-Esan OG, Osasan SA, Ojo OS. Nonneoplastic diseases of the cervix in Nigeria. A histopathological study. Afr Health Sci 2006;6:76-80.
  10. Paavonen J, Critchlow CW, DeRouen T, Stevens CE, Kiviat N, Brunham RC et al. Etiology of cervical inflammation. Am J Obstet Gynecol 1986;54:556- 64.
  11. Craig P, Lowe D. Non-neoplastic lesions of the cervix. In: Fox H, Well M, (eds). Haines and Taylor Obstetrical and Gyanecological pathology. 5th ed. Churchill Livingstone: Edinburgh; 2003. pp 273-96.
  12. Richards MJ, Angus D. Possible sexual transmission of genitourinary tuberculosis. Int J Tuberc Lung Dis 1998;2:439.
  13. Dubey K, Garewal J, Kumar N, Sharma R. Histopathological study of Non Neoplastic lesion in cervix at tertiary center. Int J Med Res Health Sci. 2016;5:42-9
  14. Philip B. Clement, Robert H. Young. Deep Nabothian Cysts of the Uterine Cervix. A Possible Source of Confusion with Minimal-Deviation Adenocarcinoma (Adenoma Malignum). Int J Gynecol Pathol 1989; 8:340-8.
  15. Fluhmann CF. Focal hyperplasia (tunnel clusters) of the cervix uteri. Obstel Gynecol 1961;17:206-14.
  16. Barut MU, Kale A, Kuyumcuoğlu U, Bozkurt M, Ağa?ayak E, ?zekinci S, Gul T. Analysis of sensitivity, specificity, and positive and negative predictive values of smear and colposcopy in diagnosis of premalignant and malignant cervical lesions. Medical science monitor: international medical journal of experimental and clinical research. 2015;21:3860.
  17. Kumar BJ, Annam V. Clinico-Pathological Study of Non-Neoplastic Lesions of Uterine Cervix with their Histopathological Categorization. International Journal of Science and Research. 2013: 2319-7064.
 

[Bhavneet Kour And Ameet Kaur. (2019); HISTOPATHOLOGICAL SPECTRUM OF NON-NEOPLASTIC LESIONS IN UTERINE CERVIX - A ONE YEAR RETROSPECTIVE STUDY. Int. J. of Adv. Res. 7 (Jul). 1040-1044] (ISSN 2320-5407). www.journalijar.com

Dr Ameet Kaur
Department of pathology, Govt. Medical College Jammu(J&K), India.

DOI:

Article DOI: 10.21474/IJAR01/9464      
DOI URL: https://dx.doi.org/10.21474/IJAR01/9464

Download Full Paper

Download PDF No. of Downloads: 54 | No. of Views: 165