SENSORY IMPROVEMENT AND REDUCTION OF NERVE THICKENING IN A LEPROSY PATIENT TREATED WITH ULTRASOUND GUIDED PERINEURAL INJECTION OF AUTOLOGOUS PLATELETRICH PLASMA: A CASE REPORT AND REVIEW OF LITERATURE.
- MBBS, Post Graduate Resident,Department of Physical Medicine and Rehabilitation (PM&R),All India Institute of Medical Sciences (AIIMS), New Delhi, India 110029.
- MBBS, MD, Senior Resident, Department of Physical Medicine and Rehabilitation (PM&R),All India Institute of Medical Sciences (AIIMS), New Delhi, India 110029.
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Background: Leprosy is caused by Mycobacterium leprae which has a certain predilection for peripheral nerves. It causes peripheral neuropathy and in the long run, it causes deformity of hands and feet. Platelet-rich plasma (PRP) which contains a variety of growth factors can stimulate neural regeneration. Materials & Methodology:A case report and review of literature (PubMed, Embase, Google Scholars, and other electronic search engines) were done. In a 45-year-old male leprosy patient, ultrasound-guided perineural autologous PRP (1 ml) injection was given at the right ulnar nerve under all aseptic precautions. Results: Right ulnar nerve showed sensory improvement especially in ulnar distribution. In ultrasound, right ulnar nerve showed mild reduction in mean cross-sectional area whereas the left ulnar nerve showed no changes. Interventions which were ethically supported by existing literature and evidences were followed and reviewed. Conclusion: To the best of our knowledge, this is the first case report where ultrasound-guided intervention was done, a long term follow-up for 4 weeks was followed and nerve thickness comparison was done. Here, PRP showed its promising role to reduce the nerve thickness and to improve the sensory function in leprosy.
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[Raktim Swarnakar and Hafis Rahman. (2019); SENSORY IMPROVEMENT AND REDUCTION OF NERVE THICKENING IN A LEPROSY PATIENT TREATED WITH ULTRASOUND GUIDED PERINEURAL INJECTION OF AUTOLOGOUS PLATELETRICH PLASMA: A CASE REPORT AND REVIEW OF LITERATURE. Int. J. of Adv. Res. 7 (Apr). 523-525] (ISSN 2320-5407). www.journalijar.com
MBBS, Post Graduate Resident, Department of Physical Medicine and Rehabilitation (PM&R), All India Institute of Medical Sciences (AIIMS), New Delhi, India 110029
