DESIGN AND DEVELOPMENT OF NEAR-INFRARED SPECTROSCOPY SYSTEM FOR MONITORING FUNCTIONAL BRAIN ACTIVITY.
- Department of Electrical and Computer Engineering, Faculty of Engineering, King Abdulaziz University, Jeddah, Saudi Arabia.
- Abstract
- Keywords
- References
- Cite This Article as
- Corresponding Author
Near infrared spectroscopy is an optical technique which can measure the spectral absorbing molecules. Recently, it has been widely researched about its applications because the method is noninvasive and safe. The technology can measure the changes in hemoglobin concentrations in the brain. NIRS is emerging as a promising tool in the cognitive neurosciences, neuro-pathology and psychological studies. Several models of NIRS instruments have been developed, but most of them are either expensive or have safety concerns when laser sources are used. We present a simplified NIRS system using continuous, bi-color LEDs emitting light at 760/840 nm, a photodiode with on-chip transimpedance amplifier having highest responsivity for the selected wavelengths. The system is controlled by two Arduino boards, each one for light sources and photodiodes. Since Arduino microcontroller boards are interfaced with the computer, analog to digital conversion (ADC) cards are not necessary in the NIRS system. A sensor probe was designed accommodating the light sources and photodectors. In the probe, LEDs and photodiodes were arranged such that a gap of 3 cm was maintained between the LED and photodiode in order to monitor the physiological activities in the cortex by measuring the hemodynamic responses. This system has been evaluated by phantom experiment. Observations from experiments suggest that this system can be used for monitoring functional activity of the human brain.
- F. Jobsis, (1977), Noninvasive, infrared monitoring of cerebral and myocardial oxygen sufficiency and circulatory parameters, Science, vol. 198, no. 4323, pp. 1264?1267.
- Cope and D. T. Delpy (1988). System for long-term measurement of cerebral blood and tissue oxygenation on newborn infants by near infra-red transillumination, Med. Biol. Eng. Comput., vol. 26, no. 3, pp. 289?294.
- Wilson B, Park Y, Hefetz Y, Patterson M, Madsen S and Jacques S (1989). The potential of time-resolved refelectance measurements for the noninvasive determination of tissue optical properties. Proc. SPIE 1064 97?106.
- Mitic, J. Kolzer, J. Otto, E. Plies, G. Solkner and W. Zinth, (1994). Time-gated transillumination of biological tissues and tissuelike phantoms, Appl. Opt., 33, 6699-710.
- Rolfe (2000). In Vivo Near Infra-Red Spectroscopy, Annual Reviews in Biomedical Engineering, vol. 2, pp. 315-354.
- Liu, H., Y. Song, K. L. Worden, X. Jiang, A. Constantinescu and R. P. Mason, (2000). Non invasive investigation of blood oxygenation dynamics of tumors by near-infrared spectroscopy, Applied Optics 39: pp.5231-5243.
- Vaithianathan, I. D. Tullis, N. Everdell, T. Leung, A. Gibson, J. Meek and D. T. Delpy (2004). Design of a portable near infrared system for topographic imaging of the brain in babies. Rev. Sci. Instrum. 75(10), pp. 3276-3283.
- Kim, S. Lee, D. Koh and B. Kim (2011). Development of wireless NIRS system with dynamic removal of motion artifacts. Biomedical Engineering Letters 1(4), pp. 254-259.
- Amol V. Patil, JavadSafaie, Hamid AbrishamiMoghaddam, FabriceWallois, and Reinhard Grebe, (2011). Experimental investigation of NIRS spatial sensitivity, Biomed. Opt. Express 2, 1478-1493.
- JuditGervain, Jacques Mehler, Janet F. Werker, Charles A. Nelson, GergelyCsibra, Sarah Lloyd-Fox, MohinishShukla, Richard N. Aslin, (2011). Near-infrared spectroscopy: A report from the McDonnell infant methodology consortium, Developmental Cognitive Neuroscience, Volume 1, Issue 1, 22-46.
- Chitnis, D., Cooper, R. J., Dempsey, L., Powell, S., Quaggia, S., Highton, D., Elwell, C., Jeremy, C. and Everdell, N. L, (2016). Functional imaging of the human brain using a modular, fibre-less, high-density diffuse optical tomography system. Biomedical Optics Express, 7, 4275?4288.
- Funane, T., Numata, T., Sato, H., Hiraizumi, S., Hasegawa, Y., Kuwabara, H., Hasegawa, K, Kiguchi, M, (2017). Rearrangeable and exchangeable optical module with system-on-chip for wearable functional near-infrared spectroscopy system. Neurophotonics, 5(1), 011007. https://doi.org/10. 1117/1.nph.5.1.011007.
- PaolPinti, IliasTachtsidis, Antonia Hamilton, Joy Hirsch, Clarisse Aichelburg, Sam Gilbert, and Paul W. Burgess, (2018). The present and future use of functional near‐infrared spectroscopy (fNIRS) for cognitive neuroscience, Ann. N. Y. Acad., Special Issue: The Year in Cognitive Neuroscience, 1-25.
[Nadr Saleh Faleh Alenzi, K. Prahlad Rao and Naif D. Alotaibi. (2019); DESIGN AND DEVELOPMENT OF NEAR-INFRARED SPECTROSCOPY SYSTEM FOR MONITORING FUNCTIONAL BRAIN ACTIVITY. Int. J. of Adv. Res. 7 (Apr). 483-488] (ISSN 2320-5407). www.journalijar.com
Department of Electrical and Computer Engineering, Faculty of Engineering, King Abdulaziz University, Jeddah, Saudi Arabia