10Aug 2018

THE STUDY OF PREVALENCE OF TUBERCULOSIS IN HIV INFECTED AND AIDS PATIENTS AND ITS CORRELATION WITH CD4 COUNT.

  • Assistant Professor, Dept. of Medicine, Agartala Govt. Medical College, Kunjaban, Agartala, Tripura.
  • Assistant Professor, Dept. of Biochemistry, Agartala Govt. Medical College, Kunjaban, Agartala, Tripura.
  • Professor, Dept. of Microbiology, Regional Institute of Medical Sciences, Imphal, Manipur.
  • Professor, Dept. of Medicine, Regional Institute of Medical Sciences, Imphal, Manipur.
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This study was conducted at Regional Institute of Medical Sciences, Imphal on 50 number of HIV/AIDS patients. Male comprised the majority of the cases (80%) and maximum number of patients were in the age group between 31 ? 40 years of age (44%) with an average age of 33.72 years. The most common route of transmission was intravenous drug use (54%) followed by heterosexual contact (34%). The most clinical features observed were fever > 1 month (68%), weight loss > 10%, body weight (56%), cough (36%), headache (28%), oral thrush and neck stiffness (24%) each and altered sensorium (20%). Co-infection with tuberculosis (TB) was recorded in 52% cases and it was more in patients with lower CD4 cell counts. In cerebrospinal Fluid (CSF) analysis protein was raised in 44% cases and reduced level of sugar was seen in 89% cases. In all the cases increased cell count with lymphocytic predominance was noted. Cryptococcus was detected in 56% cases but no Acid-Fast-Bacilli (AFB) was detected. Histopathological examination of fine needle cytology (FNAC) lymph node showed tubercular lymphadenitis in majority of the cases with positive AFB in few cases. An Extrapulmonary (61%) manifestation of tuberculosis was more than the pulmonary (27%) manifestations and the difference was more with lower CD4 cell counts (≤ 50 cells/cumm). However, the different clinical pattern of tuberculosis in relation to CD4 cell count was insignificant (p>0.05).

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[Saru kumar Debbarma, Asis Debbarma, H. Lokhendro Singh, Taruni Ng and M. Kulachandra Singh (2018); THE STUDY OF PREVALENCE OF TUBERCULOSIS IN HIV INFECTED AND AIDS PATIENTS AND ITS CORRELATION WITH CD4 COUNT. Int. J. of Adv. Res. 6 (Aug). 364-369] (ISSN 2320-5407). www.journalijar.com

Dr. Asis Debbarma
Agartala Government Medical College

DOI:

Article DOI: 10.21474/IJAR01/7529      
DOI URL: https://dx.doi.org/10.21474/IJAR01/7529

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