18Aug 2018

PREPARATION AND EVALUATION OF FUNCTIONAL DAIRY-BASED DRINK LIKE MOCHA AGAINST OXIDATIVE STRESS AND LIVER DAMAGE IN RATS.

  • Dairy Science Department, National Research Centre, Dokki, Cairo, Egypt.
  • Pathology Department, National Research Centre, Dokki, Cairo, Egypt.
  • Center of Basic Sciences (CBS), Biology Department & College Pharmaceutical Sciences and Drug Manufacturing, Misr University for Science and Technology, 6th October City, Egypt.
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Supplementation of phytochemicals and nutrients to functional dairy products are promising amd interest research for human health improvement. Functional dairy-based drink like mocha was pepared by mixing sukkari date fruits and sieved date seeds powder with milk, then its chemical compostion and sensory properties were performed. The hepatoprotective effects of the dairy-based drink to reduce toxic effects of paracetamol-induced liver damage were were studied in male rats. Blood biochemicals analysis and histopathological investigation were performed.The obtained results showed that functional dairy-based drink like mocha had gained accepted degrees for sensory properties. The activities of some serum parmeters and histopathological investigation were improved with manipulation of functional dairy-based drink like mocha and paracetamol compared with positive control. Data can be concluded that administration of a functional dairy-based drink like mocha seems to enhance the body defense and contain hepatoprotective factor against oxidative stress and liver damage in rats.

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[Ahmed M. Abdel-Salam, Abdel Razik H. Farrag, Medhat, M. Menshawy and Ahmed H. Zaghloul. (2018); PREPARATION AND EVALUATION OF FUNCTIONAL DAIRY-BASED DRINK LIKE MOCHA AGAINST OXIDATIVE STRESS AND LIVER DAMAGE IN RATS. Int. J. of Adv. Res. 6 (Aug). 623-631] (ISSN 2320-5407). www.journalijar.com

Medhat Mansour Menshawy Shoala
Assistant professor at Misr University For Science and Technology College of Pharmaceutical Sciences and Drug Manufacturing

DOI:

Article DOI: 10.21474/IJAR01/7561      
DOI URL: https://dx.doi.org/10.21474/IJAR01/7561

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