27Jul 2018

AN UNUSUAL CASE OF EXTRA FOLLICULAR ADENOMATOID ODONTOGENIC TUMOR: A CASE REPORT.

  • Professor, Department of Oral Medicine and Radiology, DA Pandu Memorial RV Dental College, Bangalore, Karnataka, India.
  • Professor and Head of Department, Department of Oral Medicine and Radiology, DA Pandu Memorial RV Dental College, Bangalore, Karnataka, India.
  • Postgraduate, Department of Oral Medicine and Radiology, DA Pandu Memorial RV Dental College, Bangalore, Karnataka, India.
  • Reader, Department of Oral Medicine and Radiology, DA Pandu Memorial RV Dental College, Bangalore, Karnataka, India.
  • Postgraduate, Department of Oral Medicine and Radiology, DA Pandu Memorial RV Dental College, Bangalore, Karnataka, India.
  • Post graduate, Department of Oral Medicine and Radiology, DA Pandu Memorial RV Dental College, Bangalore, Karnataka, India.
  • Abstract
  • Keywords
  • References
  • Cite This Article as
  • Corresponding Author

Adenomatoid odontogenic tumor (AOT) is an uncommon tumor of odontogenic origin. It has two clinicopathologic variants, namely intraosseous (follicular and extrafollicular) and extraosseous(peripheral). The extrafollicular variety is rare and shows a prevalence of 26.9%. It generally occurs in younger females with a mean age of 24 years in the anterior maxilla. A case of extrafollicular AOT with a few unusual features is being reported here. In the reported case, it occurred in an older female, 55 years of age in the anterior mandible. Conventional and advanced imaging revealed a well-defined mixed radiolucent -radiopaque lesion. Surgical enucleation was performed and the histopathological diagnosis was suggestive of extrafollicular AOT. The patient recovered well after the surgical procedure and has been on regular follow up.


  1. Friedrich RE, Scheuer HA, Zustin J (2009): Adenomatoid Odontogenic Tumor (AOT) of Maxillary Sinus: Case Report with Respect to Immunohistochemical Findings. In Vivo.; 23(1): 111-6.
  2. Philipsen HP, Reichart PA, Zhang KH, Nikai H, Yu QX (1991): Adenotnatoid odontogenic tumor: biologic
  3. profile based on 499 cases. J Oral Pathol Med; 20: 149-58.
  4. Mehkri S, Rajkumar GC, Nagesh KS, Manjunath GS (2012): Bilateral adenomatoid odontogenic tumour of the maxilla in a 2- year-old female?the report of a rare case and review of the literature. Dentomaxillofac Radiol; 41(4): 342-48 .
  5. Philipsen HP, Reichart PA (1999): Adenomatoid odontogenic tumour: facts and figures. Oral oncol; 35(2): 125-31.
  6. Philipsen HP, Samman N, Ormiston IW, Wu PC, Rcichert PA (1992): Variants of the adenomatoid odontogenic tumor with a note on tumor origin. J Oral Pathol Med; 21(8): 348-52.
  7. Gouv?a AF, Roma?ach MJ, Cunha RW, Lopes MA, Vargas PA (2009): Mandibular unilocular well-defined radiolucency. J Oral and Maxillofac Surg; 67(9): 1961-5.
  8. Kundoor VK, Maloth KN, Guguloth NN, Kesidi S (2016): Extrafollicular Adenomatoid Odontogenic Tumor: An Unusual Case Presentation. J Dent (Shiraz); 17(4): 370-74.
  9. Saluja R, Kaur G, Singh P(2013): Aggressive adenomatoid odontogenic tumor of mandible showing root resorption: A histological case report. Dent Res J (Isfahan); 10(2): 279-82.
  10. Shivali V, Pandey A, Khanna VD, Khanna P, Singh A, Ahuja T(2013): A rare case of extrafollicular adenomatoid odontogenic tumour in the posterior region of the mandible: misdiagnosed as residual cyst. J int Oral Health; 5(5): 124-8.
  11. Yilmaz N, Acikgoz A, Celebi N, Zengin AZ, Gunhan O(2009): Extrafollicular adenomatoid odontogenic tumor of the mandible: report of a case. Eur J Dent; 3(1): 71-4.
  12. Philipsen HP, Srisuwan T, Reichart PA(2002): Adenomatoid odontogenic tumor mimicking a periapical (radicular) cyst: a case report. Oral Surg Oral Med Oral Pathol Oral Radiol Endod; 94(2): 246-8.
  13. Baskaran P, Misra S, Kumar MS, Mithra R (2011): Adenomatoid odontogenic tumor?A report of two cases with histopathology correlation. J Clin imaging Sci;1(64). doi: 10.4103/2156-7514.92186. Epub
  14. Angiero F, Crippa R (2013): Adenomatoid odontogenic tumor: a case report with immunohistological profile. Anticancer research; 33(6): 2673-7.
  15. Prakasam M, Tiwari S, Satpathy M, Banda VR (2013): Adenomatoid odontogenic tumour. BMJ Case Rep; doi: 10.1136/bcr-2013-010212.
  16. Li BB, Xie XY, Jia SN (2013): Adenomatoid odontogenic tumor with fibro-osseous reaction in the surrounding tissue. J Craniofac Surg; 24(1): e100-1. doi: 10.1097/SCS.0b013e3182799005.
  17. Rezvani G, Donoghue M, Reichart PA, Pazuhi N. Suppl 2 (2015): Case Presentation of Concomitant and Contiguous Adenomatoid Odontogenic Tumor and Focal Cemento-Ossifying Dysplasia. Open Dent J; 9: 340-5.
  18. Jivan V, Altini M, Meer S, Mahomed F (2007): Adenomatoid odontogenic tumor (AOT) originating in a unicystic ameloblastoma: a case report. Head Neck pathol; 1(2): 146-9
  19. Zeitoun IM, Dhanrajani PJ, Mosadomi HA (1996): Adenomatoid odontogenic tumor arising in a calcifying odontogenic cyst. J Oral Maxillofac Surg; 54(5): 634-7.
  20. Rosa AC, Soares AB, Furuse C, Lima SR, de Ara?jo VC, Passador-Santos F (2017): A Combined Epithelial Odontogenic Tumor? A 7-Year Follow-Up Case. Head Neck Pathol; 11(4): 519-24.

[Asha R Iyengar, Seema Patil,Meghna Gohain, Subash BV, Rahamath Fatimah and Ritika Agarwal. (2018); AN UNUSUAL CASE OF EXTRA FOLLICULAR ADENOMATOID ODONTOGENIC TUMOR: A CASE REPORT. Int. J. of Adv. Res. 6 (Jul). 1161-1169] (ISSN 2320-5407). www.journalijar.com


Dr. Meghna Gohain
RAJIV GANDHI UNIVERSITY OF HEALTH SCIENCES

DOI:


Article DOI: 10.21474/IJAR01/7471      
DOI URL: https://dx.doi.org/10.21474/IJAR01/7471