CANDIDA ALBICANS: CAN IT BE A PERIODONTAL PATHOGEN?
- Professor in Department of Periodontics, College of Dental Sciences, Davangere, Karnataka ? 577004, India.
- Post Graduate Student in Department of Periodontics, College of Dental Sciences, Davangere, Karnataka ? 577004, India.
- Professor and Head of Department, Department of Periodontics, College of Dental Sciences, Davangere, Karnataka ? 577004, India.
- Professor, Department of Microbiology, Jagadguru Jayadeva Murugarajendra Medical College, Davangere, Karnataka ? 577004, India.
- Professor, Department of Microbiology, Maratha Mandal's N.G.H Institute of Dental Sciences & Research Centre, Belgaum, Karnataka ? 590019, India.
- Abstract
- Keywords
- References
- Cite This Article as
- Corresponding Author
Background: The term periodontitis encompass several polymicrobial infectious diseases of multifactorial etiology, with chronic and aggressive forms. In spite of the etiopathogenic differences between these two forms of the disease, few studies have analyzed the subgingival colonization by yeast. It is currently unclear if yeasts participate in the etiology of this disease and if they show specificity for either the chronic or aggressive forms. Aim and Objectives: To explore and quantify the presence of Candida albicans in Chronic Periodontitis (CP), Aggressive Periodontitis (AP) and Periodontally Healthy Patients (PH). Materials and Method: A total of 30 patients were included in this study, Group A:10 patients with Chronic Periodontitis, Group B:10 patients with Aggressive Periodontitis, Group C:10 patients with Periodontal Healthy Patients. The samples were collected from gingival sulcus using Universal Curette before Scaling and Root Planing (SRP) from three groups and sent to lab for investigation to identify Candida albicans by using rt-PCR. Results: The number of candida albicans were more in CP followed by AP compared to PH Patients. Conclusion: It was concluded that candida albicans were associated with CP and AP as compared to PH patients favouring further progression of periodontal disease with high occurrence of deep pockets.
- Vishakha Grover, Anoop Kapoor, Ranjan Malhotra, Virinder Singh Battu, Archana Bhatia, Sonia Sachdeva. To assess the effectiveness of a chlorhexidine chip in the treatment of chronic periodontitis: A clinical and radiographic study. Journal of Indian Society of Periodontology 2011;15 (2):139-146.
- Janaina C. O. Sardi, Cristiane Duque, Flavia S. Mariano, Iza T. A. Peixoto, Jose F. Hofling and Reginaldo B. Goncalves.Candida spp. in periodontal disease: a brief review. Journal of Oral Science, 2010;52(2):177-185.
- Urzu A, G. Hermosilla, J. Gamonal, I. Morales-Bozo, M. Canals, S. Barahona,C. CO Ccola & V. Cifuentes. Yeast diversity in the oral microbiota of subjects with periodontitis: Candida albicans and Candida dubliniensis colonize the periodontal pockets. Medical Mycology 2008; 46:783 ? 793.
- A Ja rvensivu, J Hietanen, R Rautemaa, T Sorsa, M Richardson. Candida yeasts in chronic periodontitis tissues and subgingival microbial biofilms in vivo. Oral Diseases 2004;10:106?112.
- Supriya H, Harishchandra Rai, Suhasini PD, Rajalekshmi V. Pathogenic Mechanisms of Candida Albicans in Oral Mucosa - A Review. International Journal of Health Sciences & Research 2016;6(1):489-97.
- Vanpelt E, Belkum VAV, Hays JP. Principles and Technical aspects of PCR amplification. Springer 2008; 34.
[Dr. Babitha G.A, Dr.Vangara Aditya, Dr. Shobha Prakash, Dr. Suresh.K and Dr. Kishore G.Bhat. (2018); CANDIDA ALBICANS: CAN IT BE A PERIODONTAL PATHOGEN? Int. J. of Adv. Res. 6 (Jan). 1216-1225] (ISSN 2320-5407). www.journalijar.com
