INVESTIGATION OF C. LONGA LEAVES FOR IMMUNOMODULATION: A PRELIMINARY STUDY.
- Research Scholar, (Corresponding Author), Maulana Azad National Institute of Technology, Bhopal.
- Professor, Head, Deptt. Of Chemistry, Maulana Azad National Institute of Technology, Bhopal.
- Abstract
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Turmeric (Curcuma longa) is a small rhizomatous perennial herb belonging to Zingiberaceae family originating mostly from India. The rhizome has been used widely as a spice, colouring agent and for various therapeutic properties. The leaves of C. longa plant are less explored though they possess therapeutic properties. Aim: Present study was carried out to verify the immunomodulation activity in the methanolic extract of C. longa leaves. Method: Various phytochemicals have been evaluated by the standard methods proposed by Harborne. The antioxidant activity was investigated by DPPH radical scavenging activity, NO scavenging activity and Total antioxidant activity. The antimicrobial activity was investigated by disc diffusion method. Result: The proper working of the immune cells depends on the balance of the antioxidant-oxidant balance. The investigations thus carried out suggested that C. longa leaves is a reliable source of antioxidants and is an excellent antimicrobial agent. The phytochemicals are in abundance in the leaf extracts which supports the antioxidant and antimicrobial properties. Conclusion: The antioxidants and antimicrobial activity are key to the proper functioning of the immune cells and the results clearly suggest that C. longa leaves possess decent antioxidant and antimicrobial activity thus, suggesting that C. longa leaves are potent immunomodulator.
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[Shikha Rana and Savita Dixit. (2018); INVESTIGATION OF C. LONGA LEAVES FOR IMMUNOMODULATION: A PRELIMINARY STUDY. Int. J. of Adv. Res. 6 (Jan). 309-316] (ISSN 2320-5407). www.journalijar.com