26Jun 2017

PHYTOCHEMICAL ANALYSIS OF CENTELLA ASIATICA L. LEAF EXTRACTS.

  • Post Graduate Department and Research Centre of Botany, Mahatma Gandhi College, Affiliated to University of Kerala, Kesavadasapuram, Thiruvananthapuram- 695 015, Kerala, India.
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Centella asiatica (L) commonly known as Indian Pennywort is having great medicinal value and hence used as a medicinal herb in Ayurvedic medicine. The present study intends to provide an overview of the chemical constituents present in the crude leaf extracts of C. asiatica (L) with special emphasis on their pharmacological actions. Phytochemical screening of C. asiatica (L) was studied by extracting the dried powdered leaves with four different solvents such as water, acetone, chloroform and methanol. The extracts were subjected to qualitative phytochemical analysis using standard procedures. Preliminary phytochemical analysis revealed the presence of eight compounds such as carbohydrates, tannins, steroids, terpenoids, alkaloids, flavanoids, cardiac glycosides, saponins etc. Phytochemical analysis of the dried samples were more positive for methanol extracts. The results suggest that the leaves of C. asiatica (L) are a rich source of valuable primary and secondary metabolites.

  1. Sakshi singh, Asmitha Gautham, Abhimanya Sharma and Amla Bhata. Centella asitica (L): A plant with immunse medical potential and threatened. Int. J. Pharm. Sci. Rev. Res., 4(2)2010, 0003.
  2. Vinoth S, Rajesh KP, Gurusaravanan P, Jayabalan N. 2011. Evaluation of phytochemical, antimicrobial and GC-MS analysis of extracts of Indigofera trita F. spp. Subulata (Vahl ex poir). Int. J. Agric. Res. 6(4):358-367.
  3. Centella asiatica. Retrieved 15 July 2012.
  4. Meschino Health. "Comprehensive Guide to Gotu Kola (Centella asiatica)". Retrieved 15 July 2012.
  5. "Leaf Extract Treatment During the Growth Spurt Period Enhances Hippocampal CA3 Neuronal Dendritic Arborization in Rats". Evid Based Complement Alternat Med: 349?57. September 2006.
  6. Rownak Jahan, Sophia Hossain, Syeda Seraj, Dilruba Nasrin, Zubaida Khatun, Protiva RaniDas, Md. Tabibul Islam, Ishtiaq Ahmed, Mohammed Rahmatullah., Centella asiatica (L.) Urb.: Ethnomedicinal uses and their scientific validations,-Eurasian J. Sustain. Agric. 6(4): 261-270, 2012
  7. Krishnaiah D, Sarbatly R, Bono A (2007) Phytochemical antioxidants for health and medicine: A move towards nature. Biotechnol Mol Biol Rev 1: 97-104.
  8. Mahato SB, Sen S (1997) Advances in triterpenoid research, 1990-1994. Phytochemistry 44: 1185-1236.
  9. Kappers IF, Aharoni A, van Herpen TW, Luckerhoff LL, Dicke M, et al. (2005) Genetic engineering of terpenoid metabolism attracts bodyguards to Arabidopsis. Science 309: 2070-2072
  10. H?rouart D, Sangwan RS, Fliniaux MA, Sangwan-Norreel BS (1988) Variations in the Leaf Alkaloid Content of Androgenic Diploid Plants of Datura innoxia. Planta Med 54: 14-17.
  11. Harborne J.B. (1998). Phytochemical methods, London, Chapman and Hills.
  12. Cowan MM. Plant products as antimicrobial agents. Clinical microbiology reviews 1999; 12(4): 564-
  13. Kumar R, Sharma RJ, Bairwa K, Roy RK, Kumar A. Pharmacological review on natural antidiarrhoel agents Der Pharma Chemica 2010; 2(2): 66-93.
  14. Sutar N, Garai R, Sharma US, Sharma UK. Anthelmintic activity of Platycladus orientalis leaves extract. International Journal of Parasitology Research 2010; 2(2): 1-3.
  15. Mute VM. Anthelmintic effect of Tamarind indica linn leaves juice exract on Pheretima posthuma. International journal of pharma research and development 2009; 7: 1-6.
  16. Sharma US, Sharma UK, Singh A, Sutar N, Singh PJ. In vitro anthelmintic activity of Murraya koenigii Leaves extracts. International journal of pharma and bio sciences 2010; 1(3): 1-4.
  17. Mali RG, Mahajan SG, Mehta AA. In-vitro anthelmintic activity of stem bark of Mimusops elengi Linn. Pharmacognosy Magazine 2007; 3(10): 73-76.
  18. Patel J, Kumar GS, Qureshi MS, Jena PK. Anthelmintic activity of ethanolic extract of whole plant of Eupatorium odoratum. International Journal of Phytomedicine 2010; 2: 127-132.
  19. Roy H. Preliminary phytochemical investigation and anthelmintic activity of Acanthospermum hispidum Journal of Pharmaceutical Science and Technology 2010; 2 (5): 217-221.
  20. Cruz ASP. Anthelmintic effect of Solanum lycocarpum in mice infected with Aspiculuris tetraptera. The journal of American science 2008; 4(3): 75-79.
  21. Wang GS, Han J, Zhao LW, Jiang DX, Liu YT, Liu XL. Anthelmintic activity of steroidal saponins from Paris polyphylla. Phytomedicine 2010; 17: 1102-1105.
  22. Vidyadhar S, Saidulu M, Gopal TK, Chamundeeswari D, Rao U, Banji D. In vitro anthelmintic activity of the whole plant of Enicostemma littorale by using various extracts. International journal of applied biology and pharmaceutical technology 2010; 1(3): 1119-1125.
  23. Shaibani TRMA, Phulan MS, Shiekh M. Anthelmintic activity of Fumaria parviflora (Fumariaceae) against gastrointestinal nematodes of sheep. Int. J. Agric. Biol. 2009; 11: 431?436.
  24. Bachaya HA, Iqbal I, Khan MN, Jabbar J, Gilani AH Din IU. In vitro and In vivo anthelmintic activity of Terminalia arjuna Int. J. Agric. Biol. 2009; 11: 273-278.
  25. Maniyar Y, Bhixavatimath P, Agashikar NV. Antidiarrheal activity of flowers of Ixora Coccinea in rats. J Ayurveda Integr Med 2010; 1: 287-291.

[Saranya S, Aswathy V Nair, M. Priyanka Prathapan, Neethu A.S and Neethu S. Kumar. (2017); PHYTOCHEMICAL ANALYSIS OF CENTELLA ASIATICA L. LEAF EXTRACTS. Int. J. of Adv. Res. 5 (Jun). 1828-1832] (ISSN 2320-5407). www.journalijar.com

Neethu S. Kumar
Post Graduate Department and Research Centre of Botany, Mahatma Gandhi College,

DOI:

Article DOI: 10.21474/IJAR01/4610      
DOI URL: https://dx.doi.org/10.21474/IJAR01/4610

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