21Jun 2017

INHIBITION OF MELANIN SYNTHESIS BY ASPERGILLUS FLAVUS SW-1 ISOLATED FROM SOIL.

  • Department of Pharmaceutical Engineering, Gyeongnam National University of Science and Technology.
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The goal of this study is to find bacterial strains that inhibit production of melanin owing to suppression of tyrosinase and to find products that are less irritating skin than existing chemical products. We collected various soil samples from sea and mountain and examined the activity. Among them, we identified Aspergillus flavus SW-1 to suppress production of melanin. According to a result of tyrosinase activity in the supernatant of this strain, the inhibitor was suppressed depending on concentration of the supernatant. In addition, the activity was maintained very stable up to 100℃. Taken together, since the supernatant of A. flavus SW-1 reduces biosynthesis of melanin, it is estimated to be highly applicable as a raw material for whitening functional cosmetics.

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[Yeon Jo Ha, Sam Woong Kim and Sang Wan Gal. (2017); INHIBITION OF MELANIN SYNTHESIS BY ASPERGILLUS FLAVUS SW-1 ISOLATED FROM SOIL. Int. J. of Adv. Res. 5 (Jun). 1119-1123] (ISSN 2320-5407). www.journalijar.com

Sang Wan Gal
Gyeongnam National University of Science and Technology

DOI:

Article DOI: 10.21474/IJAR01/4518      
DOI URL: https://dx.doi.org/10.21474/IJAR01/4518

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