30May 2017

A COMPARATIVE STUDY ON QUANTITATIVE PHYTOCHEMICAL ANALYSIS AND IN VITRO FREE RADICAL SCAVENGING ACTIVITYOF VARIOUS SOLVENT EXTRACTS OF TETRACERA AKARA(BURM. F.) MERR., AN ETHNOMEDICINAL PLANT USED BY KANI TRIBE OF KERALA.

  • Ethnomedicine and Ethnopharmacology Division, Jawaharlal Nehru Tropical BotanicGarden and Research Institute, Palode, Thiruvananthapuram 695 562, Kerala, India.
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Tetracera akara(Burm. f.) Merr. (Dellineaceae) is a woody climber distributed in Indo-Malayan archipelago and in India, it is found in the Western Ghats region of Kerala and Tamil Nadu. The root of T. akara is used by the Kani tribe of Kerala, India to cure various liver ailments like jaundice, inflammatory conditions, fever and also to enhance the immunity in children.The present study was aimed to scientifically validate the free radical scavenging potential of different solvent extracts of T. akara roots with different in vitro assays and also to estimate the total phenolic, flavonoid and condensed tannin contents. A significantly higher total poly phenolic content was estimated in the ethanolic fraction ofroot ofT. akara. The aqueous extracts possess significantly higher phenol and flavonoid content. Theethanolic fraction ofT. akararootexhibited 86 % inhibition against DPPH radicals at 320?g/ml concentration. Hexane and chloroform fractions showed comparatively less DPPH radical activity. In nitric oxide radical scavenging assay, all the extracts except hexane fraction showed potent activity against the free radicals and in superoxide radical scavenging assay the maximum activity was exhibited by the ethanolic fraction when compared to the standard ascorbic acid. In the present study, the antioxidant potential and free radical scavenging effects of T. akaramay be attributed to the high polyphenolic content.

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[Ragesh R Nair, S R Suja, A L Aneeshkumar, V Vilash and S Rajasekharan. (2017); A COMPARATIVE STUDY ON QUANTITATIVE PHYTOCHEMICAL ANALYSIS AND IN VITRO FREE RADICAL SCAVENGING ACTIVITYOF VARIOUS SOLVENT EXTRACTS OF TETRACERA AKARA(BURM. F.) MERR., AN ETHNOMEDICINAL PLANT USED BY KANI TRIBE OF KERALA. Int. J. of Adv. Res. 5 (May). 1907-1915] (ISSN 2320-5407). www.journalijar.com

Dr. S R. Suja
Ethnomedicine and Ethnopharmacology Division, JNTBGRI, Palode

DOI:

Article DOI: 10.21474/IJAR01/4328      
DOI URL: https://dx.doi.org/10.21474/IJAR01/4328

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