30May 2017

ROLE OF MITOMYCIN C AS ADJUNCT THERAPY FOR 3-SNIP PUNCTOPLASTY IN CORRECTING PUNCTAL STENOSIS.

  • MS, Senior Resident, Regional Institute of Ophthalmology, SCB Medical College, Cuttack.
  • Department of Ophthalmology, Veer Surendra Sai Medical College & Hospital, Burla, Orissa.
Crossref Cited-by Linking logo
  • Abstract
  • Keywords
  • References
  • Cite This Article as
  • Corresponding Author

Aim: To assess the efficacy of intraoperative mitomycin C in improving the success rate of the 3-snip punctoplasty procedure for punctal stenosis. Materials and Methods: prospective study of 36 eyes of 22 patients who underwent 3-snip punctoplasty between April 2014 to April 2015. The procedure was done without mitomycin C in 14 eyes and with mitomycin C 0.01% intraoperatively for 2 min in 22 eyes. Results: In group without mitomycin c, 4 of 14 (28.6%) eyes had complete anatomic obstruction and scarring of their puncta after surgery, compared with 0 of 22 (0.0%) eyes in group with mitomycin c. The difference was statistically significant (P=0.03). No significant complications were observed. Conclusion: Mitomycin C appears to be a safe and effective adjunct therapy in correcting punctal stenosis.

  1. Ronald K. Treatment of Lacrimal Punctal Stenosis with a One-Snip Canaliculotomy and Temporary Punctal Plugs. Arch Ophthalmol.?1988;106(7):878-9.
  2. Kopp D, Seregard S. Epiphora as a side effect of topical mitomycin c. Br J Ophthalmol. 2004 Nov; 88(11): 1422?4.
  3. Caesar H, McNab A. A brief history of punctoplasty: the 3-snip revisited. Eye. 2005; 19: 16-8.
  4. Billing K, Karagiannis A, Selva D. Punctal-canalicular stenosis associated with mitomycin-C for corneal epithelial dysplasia. Am J Ophthalmol. 2003;136(4):746?7.
  5. Ma?luf RN, Hamush NG, Awwad ST, Noureddin BN. Mitomycin C as adjunct therapy in correcting punctal stenosis. Ophthal Plast Reconstr Surg. 2002;18(4):285?8.

[Deepak Choudhury, J P Rout, P K Sharma, S Behera, J Dora and K C Tudu. (2017); ROLE OF MITOMYCIN C AS ADJUNCT THERAPY FOR 3-SNIP PUNCTOPLASTY IN CORRECTING PUNCTAL STENOSIS. Int. J. of Adv. Res. 5 (May). 1898-1901] (ISSN 2320-5407). www.journalijar.com

Deepak Choudhury
Senior Resident, Regional Institute of Ophthalmology, SCB Medical College, Cuttack, Odisha

DOI:

Article DOI: 10.21474/IJAR01/4326      
DOI URL: https://dx.doi.org/10.21474/IJAR01/4326

Download Full Paper

Download PDF No. of Downloads: 43 | No. of Views: 159