20May 2017

ASSESSMENT OF SERUM GONADOTROPINS AND PROLACTIN LEVEL AMONG OLIGO AND AZOOSPERMIA PATIENTS

  • Department of Clinical Chemistry, Faculty of Medical Laboratory Sciences,Al-Neelain University, Sudan.
  • Department of Biochemistry and Molecular Biology, Faculty of Sciences and Technology, University of Al-Neelain, Sudan.
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The aim of current study was to assess serum gonadotropins (LH and FSH) and prolactin in oligo and azoospermia patients in Khartoum State.In a cross-sectional study (n 60) oligospermia, (n 60) azoospermia and (n 60) normospermia, age range from 20 to 51 years old, were included. Sandwich immunochemistry analysis was utilized to measure serum LH, FSH and prolactin. BMI was calculated using weight/kg divided height/m2formula. Of (n 60) oligo and (n 60) azoospermia about 60% and 63.3% were found to be overweight. Compared with the normospermia the azoospermia had significantly increased FSH p-value 0.006, while other comparison analyses showed insignificant differences. Furthermore, person?s correlation revealed positive association of LH with FSH r= 0.661, p-value= 0.000, and LH with prolactin r= 0.369,p-value 0.002, while negative correlation was observed between prolactin and age r= 0.369, p-value= 0.004. In conclusion, two third of oligo and azoospermia are overweight. In azoospermia FSH is higher, thus could magnify impotence and loss of libido related complications in azoospermia patients.

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[Mohamd Elamin Abdalrazig and Amar Mohamed Ismail. (2017); ASSESSMENT OF SERUM GONADOTROPINS AND PROLACTIN LEVEL AMONG OLIGO AND AZOOSPERMIA PATIENTS Int. J. of Adv. Res. 5 (May). 480-485] (ISSN 2320-5407). www.journalijar.com

Dr. Amar Mohamed Ismail
Department of Biochemistry and Molecular Biology, Faculty of Science and Technology, Al-Neelain University - Sudan

DOI:

Article DOI: 10.21474/IJAR01/4134      
DOI URL: https://dx.doi.org/10.21474/IJAR01/4134

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