30Apr 2017

SILENT PULMONARY EMBOLISM: INCIDENCE AND RISK FACTORS IN INDIAN PATIENTS WITH LOWER LIMB DVT

  • Department of Vascular Surgery, Stanley Medical College, Chennai.
  • Department of Vascular Surgery, Thanjavur Medical College, Thanjavur.
Crossref Cited-by Linking logo
  • Abstract
  • Keywords
  • References
  • Cite This Article as
  • Corresponding Author

Objective: The aim of our study is to evaluate the incidence of silent pulmonary embolism in Indian patients with lower limb deep venous thrombosis. Materials and Methods: 44 patients with acute lower limb proximal DVT were prospectively studied with respect to various clinical factors. All patients had no respiratory symptoms and were submitted to CT pulmonary angiography for active investigation of Pulmonary Embolism. Results: 33 out of 44 patients were found to have silent PE (75%). Higher incidence of silent PE found in older age, male sex, right side involvement and unprovoked DVT. Of these risk factors, Unprovoked DVT had statistically significant higher incidence for Silent PE than patients with provoked DVT 83.38% vs. 50% (P-0.0451). Conclusion: Above data (75%) clearly shows that silent PE is very frequent in Indian patients with deep venous thrombosis. Unprovoked DVT was single most significant risk factor associated with silent PE. This very high incidence supports the need for screening and high levels of suspicion regarding this complication especially in those with proximal unprovoked DVT.


  1. Anja boc et al., Unprovoked proximal venous thrombosis is associated with an increased risk of asymptomatic pulmonary embolism , Thrombosis Research 133 (2014) 1011?1015
  2. Fenghe Li et al., Risk factors associated with the occurrence of silent pulmonary embolism in patients with deep venous thrombosis of the lower limb, Phlebology 2014, Vol. 29(7) 442?446
  3. Fuster et al., Should we look for silent pulmonary embolism in patients with deep venous thrombosis? BMC Cardiovasc Disord.?2014 Dec 8;14:178
  1. Haimovici's Vascular Surgery, 6edition
  2. Hallet?s Comprehensive.Vascular.and.Endovascular.Surgery, 2nd
  3. Jim?nez D, D?az G, Mar?n E, et al. The risk of recurrent venous thromboembolism in patients with unprovoked symptomatic deep vein thrombosis and asymptomatic pulmonary embolism. Thromb Haemost. 2006;95:562-566
  4. Kakkar et al., Pulmonary Embolism in Medical Patients: An Autopsy-Based Study, Clinical and Applied Thrombosis/ Hemostasis, Volume 14 Number 2, April 2008 159-167
  5. Krutman? et al, Risk of asymptomatic?pulmonary embolism?in patients with deep venous thrombosis, J Vasc Surg Venous Lymphat Disord.?2013?Oct;1(4):370-5.
  1. Parakh et al., Pulmonary Embolism: A Frequent Occurrence in Indian Patients with Symptomatic Lower Limb Venous Thrombosis, Asian J Surg 2006;29(2):86?91
  2. Rutherford?s vascular surgery, volume-1, 8th
  3. Stein at al., Silent Pulmonary Embolism in Patients with Deep Venous Thrombosis: A Systematic Review, The American Journal of Medicine (2010) 123, 426-431
  4. Tzoran et al., Silent pulmonary embolism in patients with proximal deep vein thrombosis in the lower limbs, Journal of Thrombosis and Haemostasis, 10: 564?571
  5. Wesley S.Moore?s Vascular and Endovascular surgery, 8th edition

[Shanmugavelayutham.C, Elancheralathan.K, Thulasikumar.G, Deepan kumar.B and Lakshmidharan. M. (2017); SILENT PULMONARY EMBOLISM: INCIDENCE AND RISK FACTORS IN INDIAN PATIENTS WITH LOWER LIMB DVT Int. J. of Adv. Res. 5 (Apr). 2135-2138] (ISSN 2320-5407). www.journalijar.com


Dr.Shanmugavelayutham
Department of Vascular Surgery, Stanley Medical College

DOI:


Article DOI: 10.21474/IJAR01/4060      
DOI URL: http://dx.doi.org/10.21474/IJAR01/4060