30Sep 2016

GC-MS ANALYSIS AND ANTIMICROBIAL ACTIVITY OF SUDANESE CYPERUS ESCULENTUS (CYPERACEAE ) FIXED OIL.

  • Sudan University of Science and Technology, Faculty of Science, Dept. of Chemistry.
  • Omdurman Islamic University , Faculty of Education, Dept. of Chemistry.
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The present study was designed to investigate the chemical constituents of Cyperus esculentus seed oil and to evaluate its potential antimicrobial activity. 21 components were detected by GC-MS analysis. Major constituents are: 9-octadecenoic acid (46.24%), hexadecanoic acid(19.27%), 9,12-octadecadienoic acid(13.62%), and methyl stearate(10.88%) . Butylated hydroxytoluene, a potent antioxidant, was detected as a minor constituent(0.10%). The antibacterial activity of the oil was evaluated via cup plate agar diffusion assay against six standard human pathogens(Gram positive: Staphylococcus aureus and Bacillus subtilis; Gram negative : Escherichia coli and Pseudomonasa aeruginosa and the fungi Candida albicans and Aspergillus niger) . The oil showed different antimicrobial responses against test organisms. It gave significant activity against the fungus :Candida albicans and partial activity against Staphylococcus aureus.It seems that the oil is a lead for further optimization.


[Abdel Karim M and Fath El-Rahman A. (2016); GC-MS ANALYSIS AND ANTIMICROBIAL ACTIVITY OF SUDANESE CYPERUS ESCULENTUS (CYPERACEAE ) FIXED OIL. Int. J. of Adv. Res. 4 (Sep). 1712-1718] (ISSN 2320-5407). www.journalijar.com


Mohamed Abdel Karim


DOI:


Article DOI: 10.21474/IJAR01/1631      
DOI URL: https://dx.doi.org/10.21474/IJAR01/1631