PREVALENCE OF ASYMPTOMATIC BACTERIURIA AND ITS ANTIMICROBIAL SENSITIVITY PATTERN AMONG PATIENTS WITH DIABETES MELLITUS AT TERTIARY HOSPITAL, BHAVNAGAR, GUJARAT.

Diabetes mellitus and its complications impose a major health burden in developing country like India. Increased silent Infection in diabetic patient is due to altered host defense mechanism, frequent hospitalization, vascular abnormality and neuropathy. This study was conducted to identify the frequency of Asymptomatic Bacteriuria and its antibiotic sensitivity pattern in diabetes people. A comparative study was carried out in 400 diabetes patients, with a group of 400 normal healthy individuals. Age and sex were matched for both control and diabetic patient. Clean voided midstream urine samples were collected into wide mouth open sterile container. The spectrum of bacteria causing asymptomatic bacteriuria and their antibiotic susceptibility profile has been noted. Asymptomatic bacteriuria was observed more commonly in patients with diabetes mellitus 11% than in non diabetic control subjects 1%. Bacteria isolated included Escherichia coli with a prevalence of 44.18%, followed by Enterococcus spp 18.6%, Klebsiella pneumonia 13.95 % and Staphylococcus aureus 9% , two cases of S. saprophyticus also isolated. Asymptomatic bacteriuria was more common in diabetes patient than non diabetic patient.