AlternationofCCl4 -Induced Oxidative Stressand Nephrotoxicity by Omega-3 in Female Albino Rats.
- MSc. Biology, Physiology/ College of Science/ University of Salahaddin – Erbil.
- MSc. Histophysiology, Lecturer, Health prevention department/Medical Technical Institute/ University of polytechnic-Erbil, Iraq.
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In the present study, twenty one female albino rats were used and they were divided in to three groups. This was carried out and designed to study the effect of omega 3 poly unsaturated fatty acid on carbon tetrachloride (CCl4) induced oxidative stress and kidney damage in female albino rats. However, the antioxidant activity of omega-3 were determined by assessing biochemical parameters (serum creatinine, urea, uric acid, and malondialdehyde(MDA)). Carbon tetrachloride caused significant increase inserumcreatinine, urea, uric acid, and MDA levelwhile, omega 3 significantly prevented the increase of the serum levels of creatinine, urea, uric acid, and MDA.
[Hawzheen K. Othman and Tahseen A. Abdullah. (2016); AlternationofCCl4 -Induced Oxidative Stressand Nephrotoxicity by Omega-3 in Female Albino Rats. Int. J. of Adv. Res. 4 (Jul). 1789-1795] (ISSN 2320-5407). www.journalijar.com
