ANTIMICROBIAL AND ANTICANCER ACTIVITIES OF SYNTHESIZED AZO COMPOUNDS OF 2-AMINO BENZOTHIAZOLE .
- Department of Chemistry and Research Centre, Women’s Christian College, Nagercoil, Tamilnadu, India.
- Department of Chemistry and Research Centre, Nesamony Memorial Christian College, Marthandam, Tamilnadu, India.
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In this investigation, azo compounds were synthesized in excellent yields via the diazotization of substituted 2-amino benzothiazole followed by coupling with aromatic compounds like 1-naphthol, 2-naphthol, resorcinol, phenol and para nitro phenol. The newly synthesized compounds were characterized by elemental analysis, IR, 1H NMR ,13C NMR and mass spectral techniques, and have been tested in vitro against a number of microorganisms in order to assess their antimicrobial properties using disk diffusion method and the minimum inhibitory concentrations (MIC) by the broth micro dilution technique. Their anticancer activity against human breast cancer cell line (MCF7) were determined by MTT assay.
[Jasmin Sugantha Malar S and Abbs Fen Reji TF. (2016); ANTIMICROBIAL AND ANTICANCER ACTIVITIES OF SYNTHESIZED AZO COMPOUNDS OF 2-AMINO BENZOTHIAZOLE . Int. J. of Adv. Res. 4 (Aug). 139-143] (ISSN 2320-5407). www.journalijar.com
