30Jun 2016

METHYLCHROMONYL LINKED BENZYLIDENES AS NOVEL PARTIAL PPAR? AGONISTS: SYNTHESIS, CHARACTERIZATION AND DOCKING STUDIES.

  • Synthetic Organic and Medicinal Chemistry Laboratory, Department of Chemistry, Punjabi University, Patiala-147002 (Pb) India.
  • Department of Basic and Applied Sciences, Punjabi University, Patiala-147002 (Pb) India.
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The synthetic and docking studies of 2-Methylchromonyl linked para/meta substituted phenyl containing thiazolidenedione (TZD), diethyl malonate (DEM), methyl acetoacetate (MAA), barbituric acid (BA) and thiobarbituric acid (TBA) analogues in an effort to develop novel peroxisome proliferator activated receptors ligands expected to exhibit PPAR? partial agonism in the management of hyperglycemia and hyperlipidemia for the treatment of type 2 diabetes is reported. Docking studies showed expected results.

[Amanjot Singh, Gagandeep Singh, Raman K. Verma, and Rajiv Mall. (2016); METHYLCHROMONYL LINKED BENZYLIDENES AS NOVEL PARTIAL PPAR? AGONISTS: SYNTHESIS, CHARACTERIZATION AND DOCKING STUDIES. Int. J. of Adv. Res. 4 (Jun). 574-582] (ISSN 2320-5407). www.journalijar.com

Dr. Rajiv Mall

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Article DOI: 10.21474/IJAR01/794      
DOI URL: https://dx.doi.org/10.21474/IJAR01/794

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