15Nov 2017

THE ROLE OF SURGERY IN SMALL CELL LUNG CANCER.

  • Department of surgery, Sher-I-kashmir Institute of of Medical Science (SKIMS),Srinagar, Jammu and Kashmir, India-190011.
  • Department of CVTS, Sher-I-kashmir Institute of of Medical Science (SKIMS),Srinagar, Jammu and Kashmir, India-190011.
  • Department of Medical Oncology, Sher-I-kashmir Institute of of Medical Science (SKIMS),Srinagar, Jammu and Kashmir, India-190011.
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OBJECTIVE: To study the role of surgery as a primary modality of treatment for patients with small cell lung cancer (SCLC). PATIENTS AND METHODS: The study was conducted in the departments of CVTS and Medical oncology SKIMS Soura from May-2008 to Sep-2010. The study was prospective /retrospective in design. All the patients (n=30) who underwent pulmonary resection for LD-SCLC from Jan-2000 to Sep-2010 were included in the study. RESULTS: The median age was 56 years (range, 35-80 years). Operations performed included lobectomy in 21, bilobectomy in 3, and pneumonectomy in 6. Postoperative therapy included chemotherapy alone in 8 patients, radiation therapy in 6, and combined chemotherapy and radiation therapy in 10, PCI was given to 7 patients. Postsurgical tumor stage was IA (n=6), IB (n=6), IIA (n=3), IIB (n=9), IIIA (n=6). Postoperative complications occurred in 20% of the patients (6/30), including 3 cases of supraventicular arrhythmia, 1 case of pneumonia, 1 case of prolonged air leakage and 1 case of wound site infection. Operative mortality was 3.3% (1/30). Patients were followed up for 1-70 months postoperatively, with a mean follow-up of 36.5 months. The 5-year survival rate according to the pathologic stage was 58.3% for patients with stage I, 25% for patients with stage II and 16.7% for patients with stage III. CONCLUSION: Pulmonary resection in patients with stage I or stage II SCLC is safe with low mortality and morbidity. Curative resection is associated with long-term survival in early stage SCLC and should be considered in selected patients.

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[Bashir Ahmad Bhat, Mushtaq Ahmad, GhNabi Lone and ShiekhAejaz Aziz. (2017); THE ROLE OF SURGERY IN SMALL CELL LUNG CANCER. Int. J. of Adv. Res. 5 (Nov). 426-431] (ISSN 2320-5407). www.journalijar.com

Bashir Ahmad Bhat
SKIMS SOURA INDIA

DOI:

Article DOI: 10.21474/IJAR01/5786      
DOI URL: http://dx.doi.org/10.21474/IJAR01/5786

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