10Aug 2017

THE ROLE OF ALLIUM SATIVUM (GARLIC) IN VARIOUS DISEASES AND ITS HEALTH BENEFITS: A COMPREHENSIVE REVIEW.

  • Department of Biochemistry& Academic consultant pharmacy, Sri Venkateswara University, Tirupati 517502.
  • Department of Biochemistry, Sri Venkateswara University, Tirupati 517502.
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Garlic belongs to the family Alliaceae , it has more than 500 species in 30 genera and the family is taxonomically intermediate between the Liliaceae and the Amaryllidaceae. It is widely distributed. Garlic contains more than one hundred biologically useful secondary metabolites, which include alliin, alliinase, allicin, S-allyl cysteine (SAC), diallyldisulphide (DADS), diallyltrisulphide (DATS) and methyl allyl trisulphide. The γ-glutamyl-S-alk(en)yl-L-cysteines are the primary sulfur compounds present in garlic. These active compounds are responsible for protection of tissue from damage and various disorders. The therapeutic potential of this plant product inhibits invasion of carcinoma, provides cardiovascular protection, lowering of cholesterol and blood pressure, anti-platelet activities, and thromboxane formation. In addition the biological activities of garlic include antibacterial, antithrombotic, antioxidant, immunomodulatory, antidiabetic and modulation of drug metabolism. The other proposed uses of garlic include hepatoprotection, antihelmenthics, antiinflammation, antifungal and wound healing. Based on our review, garlic based different ailments and concoctions can be used to alleviate a variety of health problems. Its various chemical and biological constituents contain different concentrations of organosulfur compounds to cure many diseases. Several researchers have provided a mechanism of action for many of their therapeutic effects.

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[B. J. Divya, B. Suman, L. Lakshman kumar, M.Venkataswamy, B. Eswari and K. Thyagaraju. (2017); THE ROLE OF ALLIUM SATIVUM (GARLIC) IN VARIOUS DISEASES AND ITS HEALTH BENEFITS: A COMPREHENSIVE REVIEW. Int. J. of Adv. Res. 5 (Aug). 592-602] (ISSN 2320-5407). www.journalijar.com

Prof. K. Thyagaraju
Sri Venkateswara University

DOI:

Article DOI: 10.21474/IJAR01/5094      
DOI URL: https://dx.doi.org/10.21474/IJAR01/5094

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