26Jun 2017

GC-MS ANALYSIS AND ANTIMICROBIAL ACTIVITY OF SUDANESE SORGHUM SUDANESE ( PIPER ) STAPF. FIXED OIL.

  • Sudan University of Science and Technology, Faculty of Science, Dept. of Chemistry.
  • University of Nyala , Faculty of Education, Dept. of Chemistry..
  • International University of Africa, Faculty of Pharmacy.
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The present study was undertaken to investigate the chemical constituents of Sorghum sudanese seed oil and to assess its antimicrobial activity. 25 components were detected by GC-MS analysis. Major constituents are: 9,12-octadecadienoic acid methyl ester(40.52%) ; 9-octadecenoic acid methyl ester (33.60%), hexadecanoic acid methyl ester(17.99%) . The oil was evaluated for antimicrobial activity against : (Gram positive: Staphylococcus aureus and Bacillus subtilis; Gram negative : Escherichia coli and Pseudomonasa aeruginosa and the fungus Candida albicans) . The oil showed excellent activity against all test organisms and specially against Bacillus subtilis at a concentration of 100mg/ml. At all test concentrations the oil gave significant activity against Bacillus subtilis . Excellent antifungal activity against Candida albicans was demonstrated at concentrations of 100,50 and 25 mg/ml. It seems that the oil is a lead for a potent antimicrobial agent.

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[Abdel Karim. M, Asma M. H, Mustafa. S. K and Khalid. M. S. (2017); GC-MS ANALYSIS AND ANTIMICROBIAL ACTIVITY OF SUDANESE SORGHUM SUDANESE ( PIPER ) STAPF. FIXED OIL. Int. J. of Adv. Res. 5 (Jun). 2070-2075] (ISSN 2320-5407). www.journalijar.com

Abdel Karim. M.
1. Sudan University of Science and Technology, Faculty of Science, Dept. of Chemistry

DOI:

Article DOI: 10.21474/IJAR01/4645      
DOI URL: http://dx.doi.org/10.21474/IJAR01/4645

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