15May 2017

EFFECT OF TREATMENT OF OBSTRUCTIVE SLEEP APNEA UPON COMORBID HYPERTENSION AND CARDIAC ARRHYTHMIAS.

  • Clinical Registrar, Department ofInternal medicine, SMHS Hospital Srinagar Kashmir.
  • Clinical Registrar ,Anesthesiology,Department of Health and Medical education Kashmir.
  • Clinical Registrar, Department of Gynaecology and Obstetrics,LD Hospital Srinagar Kashmir.
  • Consultant ,Department of Internal medicine,SMHS Hospital Srinagar Kashmir.
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Background: There is an established relation between obstructive sleep apnea (OSA) and various cardiovascular consequences. Objectives: To study the relation between obstructive sleep apnea, hypertension and cardiac arrhythmias and to see the effect of treatment of sleep apnea on these associations. Methods: Sixteen subjects, 11 (68.7%) males and 5 (31.2%) females with mean age of 48.12+9.3 years were diagnosed to have OSA and concomitant hypertension, cardiac arrhythmias and atrioventricular blocks. The diagnosis of OSA was established on the basis of clinical picture, Epworth Sleepiness Scale and Polysomnography. Results: Hypertension was observed in all subjects. It was found to be associated with severe OSA having apnea hypopnea index (AHI) of 31.2+2.12 bearing high statistical significance (OR 1.98, p < 0.001). Various arrhythmias included ventricular premature complexes (50%), paroxysmal supraventricular tachycardia (12.5%), atrial fibrillation (25%), and atrioventricular block was found in 12.5% patients. Treatment with nocturnal continuous positive air pressure (CPAP) significantly improved hypertension and arrhythmias and completely reversed AV blocks, bearing high statistical significance. Conclusion: Obstructive sleep apnea bears a strong relation with hypertension, cardiac arrhythmias and AV blocks and treatmentalmost abolishes these illnesses. Large sample studies are needed to further substantiate these observations.

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[Nadeem Ahmad. Tufail Ahmad Sheikh. Nihida Akhter, and G.Hassan. (2017); EFFECT OF TREATMENT OF OBSTRUCTIVE SLEEP APNEA UPON COMORBID HYPERTENSION AND CARDIAC ARRHYTHMIAS. Int. J. of Adv. Res. 5 (May). 335-339] (ISSN 2320-5407). www.journalijar.com

Tufail Ahmad Sheikh

DOI:

Article DOI: 10.21474/IJAR01/4117      
DOI URL: https://dx.doi.org/10.21474/IJAR01/4117

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