25Apr 2017

PREVALENCE AND ANTIBIOTIC RESISTANCE PATTERN OF STREPTOCOCCUS PNEUMONIAE, ISOLATED FROM INVASIVE AND NON-INVASIVE INFECTIONS IN A TERTIARY CARE HOSPITAL OF KARACHI.

  • Dow University of Health Sciences, Karachi, Pakistan, Gulzar-e-Hijri, Scheme: 33, off. University Road., Karachi, Pakistan-17000.
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Objective: To determine the frequency and susceptibility pattern of multi drug resistant Streptococcus pneumoniae isolated from clinical samples of invasive and non-invasive infections. Methods: This was a cross-sectional study conducted in the Department of Microbiology, Dow Diagnostic Reference and Research Laboratory, Karachi, Pakistan, during the period of January 2014 to October 2015. Isolation and identification of clinical isolates were performed by using standard and specific methods. Antibiotic susceptibility was performed by using Kirby Bauer method. Results: Maximum numbers of S. pneumoniae were recovered from sputum, pus and blood and a higher percentage of the organisms were isolated from females. Among non-invasive S. pneumococcal infections, children, adolescents and adults were found to be highly resistant against Cotrimoxazole, Clindamycin and Ofloxacin, respectively. In invasive S. pneumococcal infections, highest resistance was observed against Penicillin G, Cotrimoxazole and Macrolides in children, adolescents and adults, respectively. Conclusion: Emergence of antimicrobial resistance in S. pneumoniae is an alarming issue. Strict policies of infection control and surveillance programme are urgently required in order to

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[Fouzia Zeeshan Khan, Samina Baig, Samreen Zameer and Shaheen Sharafat. (2017); PREVALENCE AND ANTIBIOTIC RESISTANCE PATTERN OF STREPTOCOCCUS PNEUMONIAE, ISOLATED FROM INVASIVE AND NON-INVASIVE INFECTIONS IN A TERTIARY CARE HOSPITAL OF KARACHI. Int. J. of Adv. Res. 5 (Apr). 825-831] (ISSN 2320-5407). www.journalijar.com

FouziaKhan

DOI:

Article DOI: 10.21474/IJAR01/3882      
DOI URL: https://dx.doi.org/10.21474/IJAR01/3882

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