Effect of wheatgrass juice on lipid peroxidation , SOD activity and Catalase activity in lung cancer during chemotherapy.

A High level of oxidative stress is related with different cancer including lung cancer. Lipid peroxidation, Superoxide dismutase enzyme activity and Catalase enzyme activity are the important markers of oxidative stress. In the present study significantly increased levels of Lipid peroxidation in lung cancer patients were noticed in lung cancer patients before chemotherapy (Lipid peroxidation (6.44 ± 0.63), Superoxide dismutase (1.03 ± 0.14), Catalase (4.77±0.37) and after chemotherapy (Lipid peroxidation (7.31 ± 0.44), Superoxide dismutase (0.81 ± 0.14) , Catalase (3.89±0.27) as compared to healthy controls (Lipid peroxidation (2.11 ± 0.35) , Superoxide dismutase (1.79±0.30) , Catalase (8.10±0.42) which shows increased oxidative stress in lung cancer patients. The levels of oxidative stress were found to be increased during chemotherapy. The levels of oxidative stress were found to be decreased in lung cancer patients before chemotherapy (Lipid peroxidation (6.35 ± 0.43), Superoxide dismutase (0.99 ± 0.22), Catalase (4.66±0.44) and after chemotherapy (Lipid peroxidation (5.84 ± 0.67), Superoxide dismutase (0.87 ± 0.12), Catalase (4.18±0.31) receiving wheatgrass juice during chemotherapy. It can be conclude from the present study that increased oxidative stress is present in lung cancer patients, which further increases during chemotherapy and wheatgrass juice can act as a natural antioxidant supplement during chemotherapy to decrease oxidative stress and in effectiveness of the chemotherapy drugs.