SICKLE CELL DISEASE-INDUCED OGILVIE’S SYNDROME IN A CHILD TREATED PHARMACOLOGICALLY WITH NEOSTIGMINE: A CASE REPORT

Abdominal manifestations of vaso-occlusive crises of patient with sickle cell disease are pain and gut hypotonia as a result of ischemia of the abdominal viscera. Acute colonic pseudoobstruction is a rare, unexplained abdominal manifestation of sickle cell disease. The diagnosis needs high index of suspicion after ruling out other etiologies of similar presentation. Although there is no guideline recommendations for the optimal management, recognition and early management of this complication is important as this can avoid unnecessary surgical intervention and alters patient outcome. Here we describe a 2-years child, known to has sickle cell disease who presented with acute colonic pseudo-obstruction and was treated successfully by neostigmine. To our knowledge, this is the second such reported case in the literature.